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Opioid peptides and their receptors [PDF]
The endogenous opioid peptides belong to three groups: the endorphins, the enkephalins and the dynorphins. These three groups are clearly distinct chemical families derived from three different precursor peptides: pro-opiomelanocortin. proenkephalin and prodynorphin.
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Opioid Receptors and Endogenous Opioid Peptides
1980According to Ariens et al. (1964b), the concept of receptors was first proposed by J. N. Langley in 1905 to account for the actions of nicotine and curare at the myoneural junction, and by P. Ehrlich in 1906 to account for specific interactions between antigens and antibodies and for the selectivity of dyes for certain components of living cells.
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Pigment Cell Research, 1996
Opioid peptides and other Tyr‐NH2‐terminal peptides are substrates in vitro for mushroom and sepia tyrosinase, giving rise to synthetic melanins retaining the peptide moiety (opiomelanins). The melanopeptides are characterized by a total solubility in hydrophylic solvents at neutral and basic pH. Opioid peptides (enkephalins, endorphins, and esorphins),
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Opioid peptides and other Tyr‐NH2‐terminal peptides are substrates in vitro for mushroom and sepia tyrosinase, giving rise to synthetic melanins retaining the peptide moiety (opiomelanins). The melanopeptides are characterized by a total solubility in hydrophylic solvents at neutral and basic pH. Opioid peptides (enkephalins, endorphins, and esorphins),
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Pharmacology of Opioid Peptides
1995This book is being published at a time when opioid receptors have recently been cloned. The structural characteristics of opioid receptors and the recent advances in their molecular cloning and expression are explicated. Connecting these cloned opioid receptors with the pharmacology of opioid receptor actions is of particular importance.
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