The Role of Inflammation in Migraine Headaches: A Review
FASEB BioAdvances, Volume 7, Issue 7, July 2025.Inflammation plays a crucial role in the onset and intensity of both migraine headache symptoms and attacks. Pro‐inflammatory neurotransmitters and mediators released from neural cells and tissues that contributes to increase in nitric oxide, increase in glutamate, alterations in serotonin and dopamine levels and pain perception are involved in ...
Caryn T. Morgan, Sanah M. Nkadimeng
wiley +1 more source
Influence of opioid peptides on human neutrophil apoptosis and activationin vitro [PDF]
, 2002 Zofia Sułowska +4 more
openalex +1 more source
Tonic inhibitory control exerted by opioid peptides in the paraventricular nuclei of the hypothalamus on regional hemodynamic activity in rats [PDF]
, 2002 Andrée Lessard, Hélène Bachelard
openalex +1 more source
Allergy, Volume 80, Issue 7, Page 1831-1847, July 2025.ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga +7 more
wiley +1 more source
Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain [PDF]
, 2003 Victor J. Hruby +7 more
openalex +1 more source
British Journal of Pharmacology, Volume 182, Issue 14, Page 3044-3067, July 2025.Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Microscopy and spectroscopy approaches to study GPCR structure and function
British Journal of Pharmacology, Volume 182, Issue 14, Page 3090-3108, July 2025.Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl +2 more
wiley +1 more source
Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys. [PDF]
Eur J Pharmacol, 2019 Cornelissen JC +6 more
europepmc +1 more source
Orphanin FQ/nociceptin: an endogenous peptide agonist for the orphan opioid receptor
, 1998 David G. Lambert, David K. Grandy
openalex +1 more source
Colloquium C10: Opioid Peptides: Normal & Pathologic Signaling Mechanisms in Neurons & Glia [PDF]
, 2003 openalex +1 more source