From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]
, 2016 Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni +3 more
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Hepatoprotective Effects of Met-enkephalin on Acetaminophen-Induced Liver Lesions in Male CBA Mice
Molecules, 2014 Recent histopathological investigations in patients with hepatitis suggested possible involvement of Met-enkephalin and its receptors in the pathophysiology of hepatitis.
Roko Martinić +9 more
doaj +1 more source
Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation. [PDF]
PLoS ONE, 2012 To enhance the drug-like properties of the endogenous opioid peptide endomorphin-1 (1 = Tyr-Pro-Trp-Phe-NH(2)), the N-terminus of the peptide was modified with 2-aminodecanoic acid, resulting in compound 3.
Pegah Varamini +5 more
doaj +1 more source
Clinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer
European Journal of Heart Failure, EarlyView.Cardiac wasting‐associated cardiomyopathy in cancer patients. E/e', early diastolic filling velocity (E) over mitral annulus early diastolic tissue velocity (e'); GLS, global longitudinal strain; LV, left ventricular; LVEF, left ventricular ejection fraction; TAPSE, tricuspid annular plane systolic excursion.
Markus S. Anker +27 more
wiley +1 more source
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
, 1995 Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source
Endogenous opioids in wound-site neutrophils of sternotomy patients. [PDF]
PLoS ONE, 2012 Postoperative pain management is a critical aspect of patient care. The inflammatory state of the post-sternotomy surgical wound sensitizes nerve endings, causing pain. Unrelieved or improperly managed pain compromises wound healing.
Hamdy Awad +8 more
doaj +1 more source
ELECTROPHORESIS, EarlyView.ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont +2 more
wiley +1 more source
BmK-YA, an enkephalin-like peptide in scorpion venom. [PDF]
PLoS ONE, 2012 By screening extracts of venom from the Asian scorpion Buthus martensii Karsch (BmK) for their abilities to activate opioid receptors, we have identified BmK-YA, an amidated peptide containing an enkephalin-like sequence. BmK-YA is encoded by a precursor
Yan Zhang +5 more
doaj +1 more source
Functional Characteristics of Bioactive Millet Peptides: A Comprehensive Review
Future Postharvest and Food, EarlyView.The graphical abstract of this paper highlights the functional characteristics of bioactive peptides derived from millets. It is a promising ingredient and can be used in various applications in food, pharmaceuticals, and healthcare industries and possess biological functions.
Kouser Jan +10 more
wiley +1 more source
SNARE based peptide linking as an efficient strategy to retarget botulinum neurotoxin’s enzymatic domain to specific neurons using diverse neuropeptides as targeting domains [PDF]
, 2011 Many disease states are caused by miss-regulated neurotransmission. A small fraction of these diseases can currently be treated with botulinum neurotoxin type A (BoNT/A).
, +6 more
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