Results 81 to 90 of about 26,699 (254)

Nociceptin/Orphanin FQ Opioid Peptide-Receptor Expression in the Endometriosis-Associated Nerve Fibers-Possible Treatment Option? [PDF]

Cells, 2023
Guan Q, Velho RV, Jordan A, Pommer S, Radde I, Sehouli J, Mechsner S.   +6 more
europepmc   +1 more source

Differential behaviour of LPH‐(61–91)‐peptide in different model systems: Comparison of the opioid activities of LPH‐(61–91)‐peptide and its fragments [PDF]

, 1977
András Z. Rónai, László Gráf, József I. Székely, Zsuzsa Dunai-Kovàcs, S. Bajusz   +4 more
openalex   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source

Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening

Molecules, 2019
Morphine, oxycodone, fentanyl, and other µ-opioid receptors (MOR) agonists have been used for decades in antinociceptive therapies. However, these drugs are associated with numerous side effects, such as euphoria, addiction, respiratory depression ...
Giulio Poli, Marilisa Pia Dimmito, Adriano Mollica, Gokhan Zengin, Sandor Benyhe, Ferenc Zador, Azzurra Stefanucci   +6 more
doaj   +1 more source

Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury. [PDF]

Pharmaceutics, 2022
Zhang R, Chen M, Deng Z, Kong L, Shen B, Zhang L.   +5 more
europepmc   +1 more source

Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol

Journal of Neuroendocrinology, EarlyView.
Abstract Evidence from both clinical and preclinical studies indicates that females experience a faster progression to drug addiction and more severe addiction‐related health effects compared with males. Estradiol (E2) plays a critical role in these sex differences.
Patricia Sinclair, Navdeep S. Dhanjal, E. Blair Towers, Wendy J. Lynch, Nadine Kabbani   +4 more
wiley   +1 more source

Cardiovascular and renal effects of novel nonpeptide nociceptin opioid peptide receptor agonists. [PDF]

Br J Pharmacol, 2022
Denys IB, Gao J, Sutphen JC, Zaveri NT, Kapusta DR.   +4 more
europepmc   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

Journal of Neuroendocrinology, EarlyView.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard, Maedeh Ghasemi, Ehsan Saboory   +2 more
wiley   +1 more source

Imaging Nociceptin Opioid Peptide Receptors in Alcohol Use Disorder With [¹¹C]NOP-1A and Positron Emission Tomography: Findings From a Second Cohort. [PDF]

Biol Psychiatry, 2023
Tollefson S, Stoughton C, Himes ML, McKinney KE, Mason S, Ciccocioppo R, Narendran R.   +6 more
europepmc   +1 more source

N,N‐diallyl‐tyrosyl substitution confers antagonist properties on the κ‐selective opioid peptide [D‐Pro¹⁰]dynorphin A(1–11) [PDF]

, 1988
Jean Edouard Gairin, Honoré Mazarguil, Paul Alvinerie, Catherine Botanch, Jean Cros, Jean‐Claude Meunier   +5 more
openalex   +1 more source