Results 291 to 300 of about 2,577,172 (407)

Redefining Ketamine Pharmacology for Antidepressant Action: Synergistic NMDA and Opioid Receptor Interactions? [PDF]

Am J Psychiatry
Levinstein MR, Budinich RC, Bonaventura J, Schatzberg AF, Zarate CA, Michaelides M.   +5 more
europepmc   +1 more source

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia.

Journal of Clinical Investigation, 2014
Ji-Tian Xu, Jian-Yuan Zhao, Xiuli Zhao, Davinna L. Ligons, V. Tiwari, Fidelis E. Atianjoh, Chun-Yi Lee, Lingli Liang, Weidong Zang, D. Njoku, S. Raja, M. Yaster, Y. Tao   +12 more
semanticscholar   +1 more source

Antiobesity Medications for Older Adults—the New, the Good, the Bad, and the Unknown

Obesity, EarlyView.
ABSTRACT Objective Obesity affects 42% of older adults, with rates continuing to rise. This a complex condition influenced by non‐modifiable as well as modifiable risk factors. The disease can be treated through modifications to diet, physical activity, and behavior and more recently through antiobesity medications (AOMs) and surgery. Treatment must be
Anna Pendrey, Javier Sevilla‐Martir
wiley   +1 more source

Childhood family environment and μ-opioid receptor availability in vivo in adulthood. [PDF]

Neuropsychopharmacology
Saarinen A, Tuominen L, Puttonen S, Raitakari O, Keltikangas-Järvinen L, Hietala J.   +5 more
europepmc   +1 more source

Cebranopadol: A Novel Potent Analgesic Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist

Journal of Pharmacology and Experimental Therapeutics, 2014
K. Linz, T. Christoph, T. Tzschentke, T. Koch, K. Schiene, M. Gautrois, W. Schröder, B. Kögel, H. Beier, W. Englberger, S. Schunk, J. de Vry, U. Jahnel, S. Frosch   +13 more
semanticscholar   +1 more source

Postoperative Opioid Receipt After Parotidectomy and Associations With Persistent Opioid Use Disorder

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the association between postoperative opioid receipt and the development of persistent opioid use disorder following parotidectomy. Study Design Propensity‐matched retrospective cohort study. Setting United States. Methods The TriNetX Research Network was queried for adult patients who underwent parotidectomy from 2010
Asher C. Park, Milan P. Fehrenbach, Larry W. Wang, Oluwatobiloba Ayo‐Ajibola, Urjeet A. Patel, Sandeep Samant, Katelyn O. Stepan   +6 more
wiley   +1 more source

GPER Enhances Chronic Burn Pain via PKC-Mediated Mu-Opioid Receptor Phosphorylation in the Rostral Ventromedial Medulla. [PDF]

J Pain Res
Zhu X, Zhang Y, Zhang Q, Zhang Z.
europepmc   +1 more source

One‐Pot Synthesis of Novel β‐Carboline‐{α‐Acylaminoamide}‐Bisindole Derivatives: Antibacterial Evaluation, Molecular Docking, and Density Functional Theory Studies

ChemistryOpen, EarlyView.
A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) employing an atom‐economical one‐pot Ugi four‐component reaction and their antibacterial testing alongside docking studies, is reported. A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) is designed and synthesized employing an atom‐economical one‐pot Ugi ...
Ankit Kumar Atri, Lavanya Khullar, Gobind Kumar, Sahil Mishra, Tamanna Dua, Vinay Singh, Kusum Harjai, Parvesh Singh, Vasundhara Singh   +8 more
wiley   +1 more source

Effects of social isolation on locus coeruleus opioid receptor expression and affective behavior. [PDF]

Neurobiol Stress
Tkaczynski J, Riser J, Patel M, Shellenbarger N, Park J, Manvich D, Chandler DJ.   +6 more
europepmc   +1 more source

Mu-opioid receptors modulate noradrenaline release from the rat hippocampus as measured by in vivo microdialysis.

, 1993
Machiko Matsumoto, Mitsuhiro Yoshioka, Hiroko Togashi, Charles B. Smith, Hideya Saito   +4 more
openalex   +1 more source