Results 161 to 170 of about 75,991 (302)

Research Ethics in Stopping Opioid Use Disorder Medication. [PDF]

open access: yesJAMA Psychiatry
Weiss RD, Nunes EV, Provost SE.
europepmc   +1 more source

Core stability in women with and without chronic pelvic pain

open access: yesPM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin   +5 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco   +5 more
wiley   +1 more source

Interventions for opioid use disorder during pregnancy: a scoping review. [PDF]

open access: yesFront Psychiatry
Elmore AL   +8 more
europepmc   +1 more source

Personalized medicine and opioid use disorder

open access: yesWorld Journal of Psychiatry
Opioid use disorder (OUD) is a major public health problem affecting millions of people worldwide. Although OUD is a chronic and relapsing disorder, a variety of pharmacological and non-pharmacological interventions are available. Medication-assisted treatment of OUD generally relies on competition for opioid receptors against the addictive substance ...
openaire   +2 more sources

Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea

open access: yesRespirology, EarlyView.
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara   +1 more
wiley   +1 more source

Firearms as a Market‐Driven Epidemic: Potential Pathways to Reduce Preventable Firearm‐Related Harm in the United States

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points For half a century, firearm‐related deaths and injuries have been endemic in the United States, with COVID‐19 contributing to a record high of 48,830 deaths in 2021, an epidemic rate increase. By 2023, national trends masked a significant 10‐fold difference in firearm‐related death rates among states.
ESZTER RIMÁNYI   +8 more
wiley   +1 more source

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