Results 151 to 160 of about 75,591 (303)

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Nurse Practitioners and Opioid Use Disorder

open access: yes
Since the 1990s, the opioid epidemic has seen increase in the number of opioid-related deaths. Currently, the only approved treatment for opioid use disorder (OUD) is Medication Assisted Treatment (MAT). The need for providers to be more comfortable with
Louisa Tali, and Juanita Takeno
core  

An Age‐Friendly Approach to Caring for Chronic Lung Disease in the Ambulatory Setting

open access: yesRespirology, EarlyView.
ABSTRACT Many common chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD), have much greater prevalence among older adults and as a result, pose a substantial burden of morbidity, disability, and mortality. The care of older adults with chronic lung disease necessitates an age‐friendly approach
Angela O. Suen   +3 more
wiley   +1 more source

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

open access: yesSmall, EarlyView.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu   +5 more
wiley   +1 more source

Accessing Opioid Use Disorder Resources in Vermont

open access: yes, 2019
A handout listing contact information for opioid use disorder resources in ...
Hou, Wendy
core  

US State Policy Contexts and Mental Health Among Working‐Age Adults

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points States’ overarching policy contexts are a meaningful yet overlooked predictor of adults’ mental health, with more conservative contexts associated with worse mental health outcomes over a 30‐year period. Counterfactual analyses suggest that widespread policy shifts could meaningfully alter the national prevalence of mental distress ...
ILIYA GUTIN   +4 more
wiley   +1 more source

Early findings on home delivery of buprenorphine and retention in treatment for opioid use disorder.

open access: yes
Individuals with opioid use disorder face barriers accessing first-line pharmacotherapy. Home delivery interventions have been shown to improve medication adherence for other chronic diseases, but the relationship between buprenorphine home delivery and ...
Justin Coffey, M   +6 more
core   +1 more source

Medicaid Managed Care Plan Alignment With State Substance Use Disorder Treatment Coverage Requirements

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points States contract with Medicaid managed care plans to administer benefits for roughly 70 million Medicaid enrollees, yet little is known about how plan benefit policies for substance use disorder (SUD) treatment medications align with state requirements.
SAGE R. FELTUS   +6 more
wiley   +1 more source

Research Ethics in Stopping Opioid Use Disorder Medication. [PDF]

open access: yesJAMA Psychiatry
Weiss RD, Nunes EV, Provost SE.
europepmc   +1 more source

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