Results 151 to 160 of about 75,991 (302)

Codeine and Metabolite Concentrations in the Breastfed Neonate

Pediatric Anesthesia, EarlyView.
ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley   +1 more source

Plasma Lidocaine Concentrations During Intravenous Lidocaine Infusion Therapy in the Pediatric Population—A Scoping Review

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles, Amanda Barton, Nicholas West, Gillian Lauder   +3 more
wiley   +1 more source

Referral to and engagement in substance use disorder treatment within opioid intervention courts in New York: a qualitative study of implementation barriers and facilitators

Substance Abuse Treatment, Prevention, and Policy
Background People with opioid use disorder (OUD) are frequently in contact with the court system and have markedly higher rates of fatal opioid overdose. Opioid intervention courts (OIC) were developed to address increasing rates of opioid overdose among
Megan A. O’Grady, Katherine S. Elkington, Gail Robson, Ikenna Y. Achebe, Arthur Robin Williams, Alwyn T. Cohall, Renee Cohall, Monica Christofferson, Alejandra Garcia, Kelly S. Ramsey, Pat Lincourt, Susan Tross   +11 more
doaj   +1 more source

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz   +6 more
wiley   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 2—One Center's 15 Year Experience Improving Quality and Safety Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Pediatric ambulatory surgery has become the dominant model of surgical care in the United States, driven primarily by economic forces. There is variability in regional practice patterns, quality improvement cycles, and outcomes. Opportunity exists to overcome knowledge gaps and provide sustainable pathways of quality improvement ...
Jennifer L. Chiem, Elizabeth E. Hansen, Kayla Reece, Samuel M. Vanderhoek, Sanjay R. Parikh, Paul A. Merguerian, Lynn D. Martin   +6 more
wiley   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 1—One Center's 15 Year Evolution in Eligibility, Utilization, Efficiency, and Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Ambulatory surgery has become the dominant model of surgical care in the United States as surgical procedures increasingly shifted from inpatient to outpatient sites of practice. Similar growth in volumes has been observed in pediatric practice.
Aaron B. Low, Jennifer L. Chiem, Corrie Casey, Samuel M. Vanderhoek, Lynn D. Martin   +4 more
wiley   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 3—One Center's Evolving Regional Anesthesia Experience and Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Pediatric ambulatory surgery is the dominant model of surgical care in the U.S. and has impacted the practice of regional anesthesia (RA). Pediatric RA's use has expanded as a supplement to general anesthesia with the introduction of ultrasound.
David E. Liston, Elizabeth E. Hansen, Jennifer L. Chiem, Sean H. Flack, Daniel K. W. Low, Lynn D. Martin   +5 more
wiley   +1 more source

Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Genetic mitochondrial diseases (GMDs) are a large group of genetically and clinically heterogeneous disorders caused by defects in genes encoding mitochondrial components. GMDs are grouped into named syndromes based on clinical presentation, for example, Leigh syndrome (LS).
Brittany M. Johnson, Simon C. Johnson
wiley   +1 more source

Median Effective Volume of 0.2% Ropivacaine for Ultrasound‐Guided Axillary Brachial Plexus Block in Children Aged 6–10 Years: A Prospective Dose‐Finding Study Using Up‐and‐Down Sequential Allocation

Pediatric Discovery, EarlyView.
Purpose: This study aimed to determine the median effective volume (EV50) of 0.2% ropivacaine for ultrasound‐guided axillary brachial plexus block (ABPB) in children aged 6–10 years, using the Dixon up‐and‐down method. The EV50 was 0.350 mL/kg (95% CI: 0.197–0.362 mL/kg), calculated by isotonic regression and bootstrapping.
Tauseef Ahmad, Fei Yang, Yao Xu, Ying Yang, Huanjie Yun, Fei Xu, Yulin Xue, Yu Zhou, Zongke Shi, Yuan Shi, Shangyingying Li, Shengfen Tu   +11 more
wiley   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source