Results 181 to 190 of about 8,207 (228)
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, 2020
Nuestro objetivo es ejemplificar cómo el consumo de tóxicos y la comorbilidad con los trastornos mentales son factores de riesgo para el desarrollo de dependencia a opioides en pacientes tratados con analgésicos opioides.
Cándido Manuel García Sánchez +1 more
semanticscholar +1 more source
Nuestro objetivo es ejemplificar cómo el consumo de tóxicos y la comorbilidad con los trastornos mentales son factores de riesgo para el desarrollo de dependencia a opioides en pacientes tratados con analgésicos opioides.
Cándido Manuel García Sánchez +1 more
semanticscholar +1 more source
Opioid genetics in the context of opioid switching
Current Opinion in Supportive & Palliative Care, 2012On a population level, there is no difference in terms of efficacy or side-effects between any of the strong opioids. On an individual level, however, there is marked variation in response to opioids. This review presents some of the recent advances in opioid pharmacogenetic studies.A growing number of genes have been studied in a number of different ...
Joanne, Droney, Julia, Riley, Joy, Ross
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Clinical and Experimental Pharmacology and Physiology, 1995
SUMMARY1. The central nervous system in mammals is able to react to painful stimuli at many levels that are involved in transmission, modulation and sensation of pain. Endogenous opioid peptides and their receptors are located at key points in pain pathways, and response to pain can be modulated by local application of opioids at many sites. Mechanisms
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SUMMARY1. The central nervous system in mammals is able to react to painful stimuli at many levels that are involved in transmission, modulation and sensation of pain. Endogenous opioid peptides and their receptors are located at key points in pain pathways, and response to pain can be modulated by local application of opioids at many sites. Mechanisms
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Genetics of pain, opioids, and opioid responsiveness
Metabolism, 2010Pain is an integral part of the defense mechanisms required for survival. Several hereditary syndromes of complete or almost complete insensitivity to pain have been identified and include channelopathy-associated pain insensitivity, of which the most likely candidate gene is the α-subunit of the voltage-gated sodium channel known as Na(v)1.7.
Johanne, Tremblay, Pavel, Hamet
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Opioids, opioid receptors, and the immune response
Drug and Alcohol Dependence, 2001It is now clear that opioid receptors participate in the function of the cells of the immune system, and evidence suggests that opioids modulate both innate and acquired immune responses. We review literature here which establishes that mu-, kappa-, and delta-opioid compounds alter resistance to a variety of infectious agents, including the Human ...
L, McCarthy +4 more
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Opioids and Opioid Receptors in Peripheral Tissues
Scandinavian Journal of Gastroenterology, 1987Opioid peptides belonging to the enkephalin, beta-endorphin or dynorphin family, acting on specific opiate receptors may be found in peripheral tissues. Enkephalins have a widespread peripheral distribution, while beta-endorphin and dynorphin may be found locally in the enteric nervous system.
T, Hedner, J, Cassuto
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Medicina Paliativa, 2018
Resumen Uno de los objetivos actuales de los cuidados paliativos es la intervencion en fases mas precoces de la enfermedad. Esto supone atender a un mayor numero de pacientes ambulatorios, con un pronostico de vida mas largo y potencialmente expuestos a ...
C. paliativos +3 more
semanticscholar +1 more source
Resumen Uno de los objetivos actuales de los cuidados paliativos es la intervencion en fases mas precoces de la enfermedad. Esto supone atender a un mayor numero de pacientes ambulatorios, con un pronostico de vida mas largo y potencialmente expuestos a ...
C. paliativos +3 more
semanticscholar +1 more source
Opioid receptors and endogenous opioid peptides
Medicinal Research Reviews, 1991The field to be reviewed is now 16 years old and is based on knowledge dating back centuries. It is therefore evident that an exhaustive review is impossible. The author plans to discuss areas likely to be of interest to the readers of this journal.
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Sexologies, 2019
Resume Introduction Le recours aux antalgiques opioides au long cours peut contribuer a l’apparition de dysfonctions sexuelles (DS) feminines. Ainsi, nous avons mene une etude afin de determiner l’impact des antalgiques opioides sur la sexualite feminine.
I. Berrahal +4 more
semanticscholar +1 more source
Resume Introduction Le recours aux antalgiques opioides au long cours peut contribuer a l’apparition de dysfonctions sexuelles (DS) feminines. Ainsi, nous avons mene une etude afin de determiner l’impact des antalgiques opioides sur la sexualite feminine.
I. Berrahal +4 more
semanticscholar +1 more source
Medications for Opioid Use Disorder, Opioid Withdrawal, and Opioid Overdose
JAMAImportance Opioid use disorder (OUD) involves compulsive opioid use that causes substantial distress or impairment at work, school, or home. OUD, which is the third most prevalent substance use disorder worldwide, affected an estimated 3.7% of US adults (9 367 000) in 2022 and caused 53 774 deaths in the US in ...
Miriam T H, Harris +2 more
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