Results 251 to 260 of about 186,280 (306)

Cross‐Cohort Evidence Links KCNJ6 rs702859 to Impulsive–Compulsive Phenotypes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Impulse control disorders (ICDs) and related compulsive behaviors (CBs) are frequent non‐motor complications of Parkinson's disease (PD) with a probable genetic contribution. Objective To investigate whether genetic variants involved in reward and punishment processing are associated with impulsive–compulsive phenotypes in PD ...
Sergio García‐Díaz, Juan Francisco Martín‐Rodríguez, Laura Muñoz‐Delgado, Rafael Díaz‐Belloso, Silvia Jesús, María Teresa Periñán, Miguel Martín‐Bórnez, Ana M. Castellano‐Guerrero, Elena Ojeda‐Lepe, Daniel Macías‐García, Astrid Adarmes‐Gómez, Dolores Buiza‐Rueda, Marta Bonilla‐Toribio, Elena Iglesias‐Camacho, Manuela San‐Eufrasio, Cristina Pérez‐Calvo, Rocío Pineda‐Sánchez, Francisco Javier Gómez‐Campos, Antonio Luque‐Ambrosiani, Fátima Carrillo‐García, Pilar Gómez‐Garre, Pablo Mir   +21 more
wiley   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Characterizing trends and patterns in benzodiazepine-related toxicity deaths in Ontario: A descriptive cross-sectional study. [PDF]

PLoS One
Campbell T, Ledlie S, Leece P, Yang J, Hamzat B, Kolla G, Bozinoff N, Boyd R, Franklyn M, Smoke A, Shearer D, Gomes T.   +11 more
europepmc   +1 more source

Practice patterns of strong opioid recommendations by palliative care consultation services in German hospitals (online survey). [PDF]

BMC Palliat Care
Mueller E, Gahr S, Schnell A, Aulmann C, Roch C.   +4 more
europepmc   +1 more source

Medicine Use Preceding Fatal Poisonings Among Individuals With Bipolar Disorder. [PDF]

Basic Clin Pharmacol Toxicol
Salmelainen J, Tiihonen M, Taipale H, Lieslehto J, Tanskanen A, Tiihonen J, Hamina A.   +6 more
europepmc   +1 more source

National trends in naloxone codispensing with outpatient opioid prescriptions, 2013-2023. [PDF]

Reg Anesth Pain Med
Beck EJ, Chua KP, Gunaseelan V, Bicket M, Brummett CM, Bohnert A, Waljee JF.   +6 more
europepmc   +1 more source

Impact of treatment duration on the effectiveness of opioid analgesia: a systematic review and meta-analysis. [PDF]

Br J Gen Pract
Froentjes LS, Barrington CA, Craig RA, Morcos M, Wedman DM, Korowynk CS, Kelmer MD, Campbell FN, Garrison SR.   +8 more
europepmc   +1 more source