Results 101 to 110 of about 6,870 (262)

Ossification of the posterior longitudinal ligament: Etiology, prevalence, progression, and surgical strategies

Indian Spine Journal, 2019
Ossification of the posterior longitudinal ligament (OPLL) is characterized by replacement of the ligamentous tissue by ectopic new bone formation. OPLL often causes narrowing of the spinal canal and has been recognized as a cause of cervical myelopathy ...
Yoshiharu Kawaguchi
doaj   +1 more source

Aberrantly Expressed lncRNAs and mRNAs of Osteogenically Differentiated Mesenchymal Stem Cells in Ossification of the Posterior Longitudinal Ligament

Frontiers in Genetics, 2020
Ectopic bone formation is the chief characteristic of ossification of the posterior longitudinal ligament (OPLL). Emerging evidence has revealed that long non-coding RNAs (lncRNAs) can regulate the osteogenic differentiation of mesenchymal stem cells ...
Zhaopeng Cai, Wenjie Liu, Wenjie Liu, Keng Chen, Peng Wang, Zhongyu Xie, Jinteng Li, Ming Li, Shuizhong Cen, Guiwen Ye, Zhaofeng Li, Zepeng Su, Mengjun Ma, Yanfeng Wu, Huiyong Shen, Huiyong Shen   +15 more
doaj   +1 more source

TRIM25‐Mediated Ubiquitination and Degradation of SOX8 Promotes Ligament Fibroblast Osteogenic Differentiation and Regulates OPLL Progression by Inhibiting OSR2 Transcription

JOR SPINE, Volume 8, Issue 3, September 2025.
SOX8 is downregulated in OPLL and inhibits the osteogenic differentiation of ligament fibroblasts. TRIM25 promotes the ubiquitination and degradation of SOX8, while SOX8 transcriptionally activates OSR2 to suppress osteogenesis. The TRIM25/SOX8/OSR2 axis represents a key regulatory mechanism and a potential therapeutic target for OPLL.
Zhenqiang Wang, Yifan Tang, Changjiang Gu, Minming Lu, Ziheng Wei, Quanwei Zhou, Shengyuan Zhou, Xiongsheng Chen   +7 more
wiley   +1 more source

The HLA typing in OPLL families.

Orthopedics & Traumatology, 1988
The HLA typing in ten patients with ossification of the posterior longitudinal ligament (OPLL) in the cervical spine and their families was carried out to elucidate the genetic factor of OPLL onset. The HLA haplotypes were determined by segregation of the HLA phenotypes within a family. The results of the analysis of HLA haplotypes in the OPLL patients
Yamaguchi, Masao, Sakou, Takashi, Uehara, Hirofumi, Kishimoto, Hiroshi   +3 more
openaire   +2 more sources

AUSS Assisted ACAF Technique in the Treatment of Ossification of the Posterior Longitudinal Ligament Extending to the C2 Segment

Orthopaedic Surgery, Volume 17, Issue 9, Page 2756-2767, September 2025.
This study investigates the efficacy, safety, and feasibility of the AUSS‐assisted ACAF technique for treating cervical ossification of the posterior longitudinal ligament (COPLL) involving C2. Through surgical intervention and long‐term follow‐up of 16 relevant patients, this research demonstrates the significant therapeutic efficacy and high safety ...
Zhishen Niu, Xiaohui Ding, Bin Zhang, Qi Zhang, En Song, Jiangang Shi, Jingchuan Sun   +6 more
wiley   +1 more source

Prognostic factors for surgical outcome in spinal cord injury associated with ossification of the posterior longitudinal ligament (OPLL)

Journal of Orthopaedic Surgery and Research, 2015
BackgroundOssification of the posterior longitudinal ligament (OPLL) may increase the risk of spinal cord injury (SCI) with various neurological deficits after minor trauma.
Soon-Young Kwon, J. Shin, Ji Hae Lee, Ho-Cho Woo   +3 more
semanticscholar   +1 more source

Dura Vibration Difference Between PTP Bone Resection and Upper Facet Joints En Bolc Resection in Posterior Thoracic Decompression

Orthopaedic Surgery, Volume 17, Issue 9, Page 2735-2743, September 2025.
The patient was a 52‐year‐old male with OLF (T9‐T11). (A and B) Preoperative MRI and CT sagittal reconstruction images (* ossified ligamenta flavum); (C) CT coronal reconstruction images showed the positional relationship between the OLF and the POT (2, 6 are the upper POT, * are the OLF, 3, 5 are the lower POT).
Rui Wang, Yingjie Zheng, Weixiang Ke, Junfei Hu, Guangming Xia, Yu Dai, Yuan Xue   +6 more
wiley   +1 more source

Correlation Between Facet Tropism and Ossification of the Posterior Longitudinal Ligament in the Cervical Spine

Global Spine Journal
Study Design Retrospective cohort study. Objectives To explore the correlation between Facet Tropism (FT) and OPLL in cervical spine. Methods One-hundred patients with OPLL of cervical spine and one-hundred normal participants without OPLL or cervical ...
Hao Zhou MD, Jianxi Wang MD, Wenyu Zhang MD, Chenfei Gao MD, Bo Hu MD, Genjiang Zhen MD, Xingyu Li MD, Hui Wang MD, Wen Yuan MD, PhD, Huajiang Chen MD, PhD, Lei Liang MD, PhD   +10 more
doaj   +1 more source

Long-Term Follow-Up of Patients with Neck Pain Associated with Ossification of the Posterior Longitudinal Ligament Treated with Integrative Complementary and Alternative Medicine: A Retrospective Analysis and Questionnaire Survey

Journal of Pain Research, 2022
Jin Namgoong,1 Yun-Ha Lee,1 Ah Ra Ju,1 Jiwon Chai,1 DongJoo Choi,1 Hyo Jung Choi,1 Ji-Yeon Seo,1 Kyoung Sun Park,2 Yoon Jae Lee,1,3 Jinho Lee,2 In-Hyuk Ha1,3 1Bucheon Jaseng Hospital of Korean Medicine, 414 KR in Sangdong, Bucheon-si, Gyeonggi-do ...
Namgoong J, Lee YH, Ju AR, Chai J, Choi D, Choi HJ, Seo JY, Park KS, Lee YJ, Lee J, Ha IH   +10 more
doaj  

Bone Cement Augmentation for Cervical Vertebrae‐Ossification of the Posterior Longitudinal Ligament Complex Contributes to Anterior Controllable Antedisplacement and Fusion in Patients With Osteoporosis

Orthopaedic Surgery, Volume 17, Issue 8, Page 2479-2485, August 2025.
Anterior controllable antedisplacement and fusion (ACAF) is an effective strategy in treating cervical ossification of the posterior longitudinal ligament (C‐OPLL). The controllable antedisplacement of vertebrae‐OPLL complex (VOC) through screws is both the most critical and technically challenging procedure.
Qilin Lu, Xugui Li, Bin Zhang, Jiangang Shi, Jingchuan Sun   +4 more
wiley   +1 more source