Results 91 to 100 of about 3,495,162 (348)

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Prevalence of Cooking with Polluting Fuels and Association with Elevated Blood Pressure Among Adults in Port au Prince, Haiti: A Cross-Sectional Analysis

Global Heart
Background: Cooking with polluting fuels is common in low- and middle-income countries and may impact blood pressure, yet data on this association in urban Haiti is limited.
Rehana Rasul, Rodney Sufra, Marie Christine Jean Pierre, Reichling St. Sauveur, Vanessa Rouzier, Joseph Inddy, Erline Hilaire, Fabiola Preval, Lily D. Yan, Nour Mourra, Anju Ogyu, Daniella M. Pierre, Jean William Pape, Denis Nash, Margaret L. McNairy   +14 more
doaj   +1 more source

Incidence and Prevalence of Opportunistic and Other Infections and the Impact of Antiretroviral Therapy Among HIV-infected Children in Low- and Middle-income Countries: A Systematic Review and Meta-analysis

Clinical Infectious Diseases, 2016
This meta-analysis demonstrates a substantial decrease in the risk of most opportunistic infections with antiretroviral therapy (ART) use in human immunodeficiency virus-infected children in low- and middle-income countries and estimated cost savings ...
M. B-Lajoie, Olivier Drouin, G. Bartlett, Q. Nguyen, A. Low, Georgios Gavriilidis, P. Easterbrook, L. Muhe   +7 more
semanticscholar   +1 more source

Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Multimorbidity is increasingly prevalent in lower‐ and middle‐income countries. Health‐related quality of life (HRQOL) has been inversely associated with multimorbidity but is understudied in lower‐ and middle‐income countries.
Shalom Sabwa, Vanessa Rouzier, Rodney Sufra, Reichling St. Sauveur, Nour Mourra, Rehana Rasul, Joseph Inddy, Lily D. Yan, Madeline Sterling, Laura Pinheiro, Marie Deschamps, Jean William Pape, Margaret L. McNairy   +12 more
doaj   +1 more source

Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis

Annals of the Rheumatic Diseases, 2015
Objectives To evaluate the risk of opportunistic infections (OIs) in patients with rheumatoid arthritis (RA) treated with tofacitinib. Methods Phase II, III and long-term extension clinical trial data (April 2013 data-cut) from the tofacitinib RA ...
K. Winthrop, S. Park, A. Gül, M. Cardiel, J. Gómez-Reino, Yoshiya Tanaka, K. Kwok, T. Lukić, E. Mortensen, D. P. D. León, R. Riese, H. Valdez   +11 more
semanticscholar   +1 more source

Functional models from limited data: A parametric and multimodal approach to anatomy and 3D kinematics of feeding in basking sharks (Cetorhinus maximus)

The Anatomical Record, EarlyView.
Abstract Basking sharks, Cetorhinus maximus (Gunnerus, Brugden [Squalus maximus], Det Kongelige Norske Videnskabers Selskabs Skrifter, 1765, vol. 3, pp. 33–49), feed by gaping their mouths and gill slits, greatly reorienting their cranial skeletons to filter food from water.
Tairan Li, Mike Schindler, Martha Paskin, Venkata A. Surapaneni, Elliott Scott, Sabine Hauert, Nicholas Payne, David E. Cade, Jeremy A. Goldbogen, Frederik H. Mollen, Daniel Baum, Sean Hanna, Mason N. Dean   +12 more
wiley   +1 more source

A contribution to the anatomy of two rare cetacean species: The hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica)

The Anatomical Record, EarlyView.
Abstract The anatomical description of the hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica) remains largely unexplored, due to limited specimen availability and preservation challenges. This study employed digital imaging techniques, conventional histology, and computed tomography to provide visualization of
Jean‐Marie Graïc, Tommaso Gerussi, Bruno Cozzi, Rebecca M. Boys, Brian Chin Wing Kot, Matthew R. Perrott, Kane Fleury, Tabris Yik To Chung, Henry Chun Lok Tsui, Emma Burns, Trudi Webster, Stuart Hunter, Emma L. Betty, Odette Howarth, Carolina Loch, Sophie White, Steve Dawson, William Rayment, Ros Cole, Derek Cox, Tom Waterhouse, Hannah Hendriks, Anton van Helden, Muriel Johnstone, Ramari Oliphant Stewart, R. Ewan Fordyce, Karen A. Stockin   +26 more
wiley   +1 more source

IMMUNOMODULATORS IN OPPORTUNISTIC INFECTIONS TREATMENT

Инфекция и иммунитет, 2014
. The immune status and the level of specific antibodies to Cytomegalovirus (121 patients) or Mycoplasma pneumoniae (129 patients) were tested in 250 patients aged 19–56 years old. This cohort was divided for three groups. Seventy eight patients with low
A. P. Toptygina, G. V. Bobyleva, V. A. Alioshkin   +2 more
doaj   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Cost analysis of screening according to ECCO guidelines for prevention of opportunistic infections in infliximab-treated ibd patients [PDF]

, 2011
Andrew J. Metz, Tim Elliott, B. Hull, John S. Duncan, M Sastrillo, Frank M. Smith, Jeremy Sanderson, Peter M. Irving   +7 more
openalex   +1 more source