Results 101 to 110 of about 140,857 (270)

The contact process with semi-infected state on the complete graph [PDF]

open access: yesarXiv, 2017
In this paper we are concerned with the contact process with semi-infected state on the complete graph $C_n$ with $n$ vertices. In our model, each vertex is in one of three states that `healthy', `semi-infected' or `wholly-infected'. Only wholly-infected vertices can infect others. A healthy vertex becomes semi-infected when being infected while a semi-
arxiv  

Prevalence and genetic characterization of Giardia lamblia in relation to diarrhea in Limpopo and Gauteng provinces, South Africa

open access: yesParasite Epidemiology and Control, 2020
Background: Very few studies have determined the prevalence and assemblage distribution of Giardia lamblia in South Africa. The present study aimed to ascertain the prevalence of G.
Amidou Samie   +6 more
doaj  

Classifying Latent Infection States in Complex Networks [PDF]

open access: yesarXiv, 2014
Algorithms for identifying the infection states of nodes in a network are crucial for understanding and containing infections. Often, however, only a relatively small set of nodes have a known infection state. Moreover, the length of time that each node has been infected is also unknown.
arxiv  

Diversity‐Oriented Synthesis and Antibiofilm Evaluation of Furan‐2‐Carboxamides

open access: yesChemMedChem, EarlyView.
Navigating through the chemical space of antibiofilm agents! Furan‐2‐carboxamides inhibit the production of this extracellular shield in Pseudomonas aeruginosa by modulating the linkers and substituents of the central core. The discovery offers a solution to the metabolically unstable antibiofilm agents based on furanones, leading to the design of more
Ana C. Muñoz‐Estrada   +4 more
wiley   +1 more source

Estimation of species relative abundances and habitat preferences using opportunistic data [PDF]

open access: yesarXiv, 2017
We develop a new statistical procedure to monitor, with opportunist data, relative species abundances and their respective preferences for dierent habitat types. Following Giraud et al. (2015), we combine the opportunistic data with some standardized data in order to correct the bias inherent to the opportunistic data collection. Our main contributions
arxiv  

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

open access: yesChemMedChem, EarlyView.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar   +10 more
wiley   +1 more source

Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study

open access: yesHIV/AIDS: Research and Palliative Care, 2021
Abrham Shitaw Tewachew,1 Wassie Negash Mekonnen,2 Abinet Dagnaw Mekuria,2 Yosef Eshetie Amare3 1Department of Medicine, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Public Health, Institute of
Tewachew AS   +3 more
doaj  

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr   +12 more
wiley   +1 more source

Targeted Suppression of Peptide Degradation in Ag‐Based Surface‐Enhanced Raman Spectra by Depletion of Hot Carriers

open access: yesSmall, Volume 18, Issue 52, December 28, 2022., 2022
Biosample degradation significantly limits the application of surface enhanced Raman spectroscopy (SERS) and often causes mis‐assignments of spectra. Using iodide solutions not only suppresses sample degradation in SERS and provides signal similar to standard Raman spectra, it also provides insight into the photocatalytic mechanisms behind the ...
Xiaobin Yao   +13 more
wiley   +1 more source

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