Results 41 to 50 of about 154,581 (303)

Late presentation of Pneumocystis jirovecii pneumonia after renal transplant: A case report

Medical Mycology Case Reports, 2018
The highest risk of opportunistic infections is from 1 to 6 months post-transplant. We report a rare case of Pneumocystis jirovecii pneumonia in a renal transplant recipient only on maintenance immunosuppression eleven years after transplant without ...
Prithiv Prasad, Kevin Bryan Lo, Pradhum Ram   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Wind Power Performance Optimization Considering Redundancy and Opportunistic Maintenance

Mendel, 2018
In This paper the redundancy and imperfect opportunistic maintenance optimization of a multi-state weighted k-out-of-n system is formulated. The objective is to determine the k-out-of-n system redundancy level and the maintenance strategy which will ...
Hadi Abdollahzadeh Sangroudi
doaj   +1 more source

A Double-Layer Optimization Maintenance Strategy for Photovoltaic Power Generation Systems Considering Component Correlation and Availability

Frontiers in Energy Research, 2022
Aiming at the problem that the maintenance method based on the status information of the photovoltaic power generation system cannot effectively reflect the influence of the comprehensive correlation of the components on the maintenance strategy, on the ...
Xubin Li, Wei Chen, Huan Lei, Tingting Pei, Xiping Pei   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The opportunistic replacement and inspection problem for components with a stochastic life time [PDF]

, 2011
The problem of finding efficient maintenance and inspection schemes in the case of components with a stochastic life time is studied and a mixed integer programming solution is proposed.
Bohlin, Markus, Ekman, Jan, Holst, Anders   +2 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Opportunistic Maintenance Modeling of Large-Scale Hot Rolling Production Line Based on Maintenance Priority and Dual Variable Time Window

Shanghai Jiaotong Daxue xuebao
To solve the problem of differential maintenance demand caused by daily dynamic maintenance and periodic replacement of support rolls in large-scale hot rolling lines, a maintenance priority rule is introduced to identify maintenance judgment order of ...
MAO Wenxin, ZHOU Xiaojun
doaj   +1 more source

A step-wise approach to a national hepatitis C screening strategy in Malaysia to meet the WHO 2030 targets: proposed strategy, coverage, and costs [PDF]

, 2019
In Malaysia, more than 330 000 individuals are estimated to be chronically infected with hepatitis C virus (HCV), but less than 2% have been treated to date.
Azzeri, Amirah, Dahlui, Maznah, Hecht, Robert, Hiebert, Lindsey, McDonald, Scott A, Mohamed, Rosmawati, Shabaruddin, Fatiha, Soe-Lin, Shan, Syed Mansor, Syed Mukhtar   +8 more
core   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source