Results 41 to 50 of about 2,244,875 (311)
HBP Leaders' Commitment to Equal Opportunities and Inclusiveness [PDF]
, 2023 Enhancing equal opportunities for all affiliated personnel, at all career levels and functions, with a specific focus on gender is difficult to achieve complex large-scale science.
The Human Brain Project, Diversity and Equal Opportunities Committee +1 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Radiologists’ experiences and perceptions regarding the use of teleradiology in South Africa
South African Journal of Radiology, 2023 Background: Teleradiology was implemented in South Africa in 1999, but the subsequent uptake was low and slow. The onset of the coronavirus disease 2019 (COVID-19) pandemic catapulted South African healthcare into the arena of teleradiology. This created
Renata Schoeman, Mario Haines
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Experiments, Opportunities and Provocations in Speculative Biography: Opening and Overview
, 2021 This opening chapter presents the aims of, and questions driving, the edited collection Speculative Biography: Experiments, Opportunities and Provocations. In addition to defining the term speculative biography, the chapter outlines the rationale for the
Lindsey, Kiera +3 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Thermal shakedown in granular materials with irregular particle shapes
Scientific ReportsGranular materials with irregular particle shapes undergo a myriad of temperature variations in natural and engineered systems. However, the impacts of cyclic temperature variations on the mechanics of granular materials remain poorly understood ...
Yize Pan +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Big Data and Cognitive Computing, 2023 ChatGPT, a conversational AI interface that utilizes natural language processing and machine learning algorithms, is taking the world by storm and is the buzzword across many sectors today.
Hossein Hassani, Emmanuel Sirmal Silva
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source