Results 61 to 70 of about 2,244,875 (311)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Storing CO2 while strengthening concrete by carbonating its cement in suspension
Communications MaterialsCement is a key constituent of concrete and offers a large sequestration potential of carbon dioxide (CO2). However, current concrete carbonation approaches are hindered by low CO2 capture efficiency and high energy consumption, often resulting in ...
Xiaoxu Fu +3 more
doaj +1 more source
Journal of ICTUrban expansion and the corresponding increase in land surface temperature (LST) are significant environmental concerns worldwide. In Malaysia, the urbanisation rate has increased dramatically from 1970 to 2020, according to the Statistics Department ...
Nur Suhaili Mansor +5 more
doaj +1 more source
Opportunities for upgrading the banana value chain in Uganda
, 2005 Journal of continuing Education and Extension, 2015; 6 (1): 826-843As one of the major staple foods in Uganda, the banana industry is important for providing . fi)od and income to producers and other value chain actors.
Tumwesigye, G. +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
MethodsXThere is increasing recognition of the need for researchers to collect and report data that can illuminate health inequities. In pain research, routinely collecting equity-relevant data has the potential to inform about the generalisability of findings ...
Emma L. Karran +9 more
doaj +1 more source
Reumatismo, 2011 Nel precedente numero di questa rubrica riconoscevo la presenza di tre grossi limiti nella creazione dell’offerta di lavoro nel settore in Italia: • L’ignoranza da parte delle amministrazioni sanitarie delle dimensioni sociali, delle invalidità e dei costi derivanti dalle malattie reumatiche; • la mancanza di una vera concorrenza all’interno del ...
openaire +7 more sources
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, 2019 "Publication date: 12/18"--Unnumbered page
Opportunities for Ohioans with Disabilities
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source