Results 91 to 100 of about 4,672,355 (357)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Asian Americans and Pacific Islanders and Opportunity [PDF]
, 2006 Asian Americans and Pacific Islanders face many barriers to opportunity, but a full assessment of opportunity among Asian Americans and Pacific Islanders is lacking because federal data are often missing or inadequately capture the diversity within these
core
The Geography of Rural Educational Opportunity
RSF: The Russell Sage Foundation Journal of the Social Sciences, 2022 We use nearly 430 million standardized test scores, including test scores from more than 6,500 rural school districts, to describe educational opportunity in rural America.
Jessica Drescher +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Factors influencing the entrepreneurial engagement of opportunity and necessity entrepreneurs
Eurasian Business Review, 2016 The scholarly literature often distinguishes between so-called opportunity and necessity entrepreneurship and between “pull” and “push” motivations. Despite the pervasive use of this terminology, empirical analyses are mostly based on a single country ...
Peter van der Zwan +3 more
semanticscholar +1 more source
Social Inclusion, 2018 Scholarly findings suggest that immigrants in Western countries, in general, participate less in politics and show lower levels of political efficacy than native-born citizens.
Per Adman, Per Strömblad
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Resistance Economy, Turning the Sanction to Opportunity [PDF]
International Journal of Management, Accounting and Economics, 2014 In recent years, the term Resistance economy is raised by the great Leader of Iran and then it is turned into the common concept of political economy issues.
Ali Keshavarzi, Sarvoldin Fathi
doaj
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source