Results 51 to 60 of about 4,579,259 (328)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Opportunity Costs of Remaining a Book Discipline [PDF]

open access: yes, 2015
Essay suggests that technological shifts impacting scholarly communication should encourage us to question the opportunity costs of insisting on maintaining the 100,000 word monograph as the core unit of published scholarship acknowledged for purposes of
Putnam, Lara
core  

Land use decision modeling with opportunity costs

open access: yesRozwój Regionalny i Polityka Regionalna
The purpose of this paper is to propose a model approach to the land development decision-making process that formally incorporates opportunity costs.
Paulina Badura
doaj   +1 more source

Analyzing economic viability of implementing Redd+ in India: Cost benefit approach

open access: yesEnvironment Conservation Journal, 2017
The paper seeks to find the economic viability of implementing REDD+, a voluntary market mechanism which involves incentivizing developing countries to stop deforestation and forest degradation in exchange of payment by the developed countries, to ...
Bibhu Prasad Sahoo, Karman Kaur
doaj   +1 more source

Economic Resilience of EU Dairy Farms: An Evaluation of Economic Viability

open access: yesAgriculture, 2021
The economic viability of dairy farms is a measure of their ability to survive and grow. Its measurement is particularly important in periods of changes taking place in the environment of these entities.
Artur Wilczyński, Ewa Kołoszycz
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Practical Alternatives to Estimate Opportunity Costs of Forest Conservation [PDF]

open access: yes, 2017
Numerous studies have shown the merits of targeting the costs of conservation besides environmental benefits and aligning payments for ecosystem services with incurred costs.
Wunscher, Tobias   +2 more
core   +1 more source

Priority setting: the importance of incorporating opportunity costs

open access: yesIsrael Journal of Health Policy Research, 2012
This article is a comment on Ofra Golan and Paul Hansen’s framework for health technology prioritization that they suggest could be developed and used by the committee selecting new technologies for Israel’s health basket.
Norheim Ole Frithjof
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Understanding Opportunity Costs and the Economist’s View: A Response to Scriven's "The Economist's Fallacy"

open access: yesJournal of MultiDisciplinary Evaluation, 2008
Of course, the concept of opportunity costs has generally remained in the domain of economists and its understanding and acceptance are not universal in other fields, including evaluation.
Brad R. Watts
doaj   +1 more source

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