Results 171 to 180 of about 120,355 (268)

From designer babies to edited food: comparing public attitudes toward CRISPR technology and gene editing in Japan and the United States. [PDF]

BMC Med Ethics
Matsuyama M, Hartwig T, Yokoyama HM, Kinoshita S, Ikkatai Y, Takanashi N.   +5 more
europepmc   +1 more source

The square of opposition.

Notre Dame Journal of Formal Logic, 1976
openaire   +2 more sources

Trubetzkoy's bilateral opposition and multilateral opposition

, 1997
Dos de las clases de ‘oposiciones fonológicas’ propuestas por Trubetzkoy (1939), ‘oposición bilateral’ y ‘oposición multilateral’, frecuentemente se interpretan de manera errónea como oposiciones fonológicas. La discusión en este trabajo gira en torno a los ejemplos de ‘oposición bilateral’ y ‘oposición multilateral’ que L.M.
openaire   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Family-Focused Digital Mental Health Care for Pediatric Oppositional Symptoms and Caregiver Outcomes: Retrospective Analysis. [PDF]

JMIR Pediatr Parent
Lawrence-Sidebottom D, McAlister K, McCutchen D, Roots M, Huberty J.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Adaptive memory-based opposition and midpoint mutation in black winged kite algorithm for global optimization and engineering applications. [PDF]

Sci Rep
P R, M J.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Optimization of split-ring resonator slots using levy-opposition-enhanced Newton Raphson method for high-gain UWB Vivaldi antenna design. [PDF]

Sci Rep
Özmen H, Izci D, Rizk-Allah RM, Ekinci S, Dalarsson M.   +4 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source