Results 51 to 60 of about 115,781 (240)
Created on January 21, 2011 in the aftermath of riots across the country, the National Coordination for Change and Democracy (NCCD) called for forces to rally and denounce the repression. Whether collectively or individually, formally organized or not, a
Layla Baamara
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The article is devoted to the transformation of both the ruling elite and the Official Opposition in the United Kingdom in the period 2015–2022 and its reflection in Britain’s diplomatic practices.
A. A. Malinina
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Pouvoir et opposition en Algérie : vers une transition prolongée ?
In the Algerian political system, organized and structured opposition remains subject to the changes, obstacles, progress and setbacks of the governing political regime.
Louisa Dris-Aït Hamadouche +1 more
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This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Resumen El presente estudio pretendió analizar la capacidad de lanzamiento general y específica en función de las etapas de vida deportiva. Con dicho objetivo, ciento seis jugadores de balonmano de diferentes edades y niveles competitivos fueron ...
Jesús Rivilla-Garcia +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
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Tempo di inquietudini. La segreteria Natta raccontata da L’Unità (1984-1989)
The paper aims to describe the years of Alessandro Natta as Secretary of the Italian Communist Party from 1985 to 1988. It reconstructs the self-representation of the party’s leadership through its newspaper.
Michelangela Di Giacomo si è addottorata presso l’Università di Siena; è Borsista presso l’Institut d’Estudis Catalans di Barcellona e Cultore della materia presso il Dispi-Università di Siena. Ha vinto con le sue tesi il premio della Presidenza della Repubblica/Fondazione Spadolini nel 2012 e di quello del Senato della Repubblica nel 2009.
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