Results 71 to 80 of about 15,771 (212)

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

open access: yesAdvanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong   +10 more
wiley   +1 more source

Molecular evidence that only two opsin subfamilies, the blue light- (SWS2) and green light-sensitive (RH2), drive color vision in Atlantic cod (Gadus morhua). [PDF]

open access: yesPLoS ONE, 2014
Teleosts show a great variety in visual opsin complement, due to both gene duplication and gene loss. The repertoire ranges from one subfamily of visual opsins (scotopic vision) including rod opsin only retinas seen in many deep-sea species to multiple ...
Ragnhild Valen   +4 more
doaj   +1 more source

Molecular logic behind the three-way stochastic choices that expand butterfly colour vision. [PDF]

open access: yes, 2016
Butterflies rely extensively on colour vision to adapt to the natural world. Most species express a broad range of colour-sensitive Rhodopsin proteins in three types of ommatidia (unit eyes), which are distributed stochastically across the retina.
Arikawa, Kentaro   +5 more
core   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

open access: yesAdvanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber   +12 more
wiley   +1 more source

Long-wavelength sensitive visual pigments of the guppy (): six opsins expressed in a single individual [PDF]

open access: yes, 2007
Background The diversity of visual systems in fish has long been of interest for evolutionary biologists and neurophysiologists, and has recently begun to attract the attention of molecular evolutionary geneticists. Several recent studies
Weadick, Cameron J, Chang, Belinda S
core   +2 more sources

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

open access: yesAdvanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi   +15 more
wiley   +1 more source

A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling

open access: yesBMC Biology, 2018
Background Animal opsins are light-sensitive G-protein-coupled receptors (GPCRs) that enable optogenetic control over the major heterotrimeric G-protein signaling pathways in animal cells.
Edward R. Ballister   +3 more
doaj   +1 more source

Long-wave opsin involved in body color plastic development in Nilaparvata lugens

open access: yesBMC Genomics, 2023
Background As one of the components of visual photopigments in photoreceptor cells, opsin exhibits different spectral peaks and plays crucial roles in visual function. Besides, it is discovered to evolve other functions despite color vision.
Jia-Bao Lu   +6 more
doaj   +1 more source

Evolution of opsins and phototransduction [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2009
Opsins are the universal photoreceptor molecules of all visual systems in the animal kingdom. They can change their conformation from a resting state to a signalling state upon light absorption, which activates the G protein, thereby resulting in a signalling cascade that produces physiological responses.
Yoshinori, Shichida, Take, Matsuyama
openaire   +2 more sources

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

open access: yesAdvanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui   +8 more
wiley   +1 more source

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