Results 71 to 80 of about 9,704 (180)

Effect of Escherichia coli endotoxin on Archachatina marginata haemolymph coagulation system [PDF]

, 2010
The effect of _E. coli_ endotoxin on the heamolymph coagulation response of _Archachatina marginata_ was studied. Heamocyte Lysate(HL), Haemocyte Lysate Supernatant(HLS) and Haemocyte Lysate Debris (HLD) were exposed to _Escherichia coli_ endotoxin ...
Adenike Oladiji, Musa Salawu, Musa Yakubu, Nasiru Muhammad, Oyelola Oloyede   +4 more
core   +1 more source

Chitosan–Alginate Polyelectrolyte Systems: From Classical Release Models to the D‐PARMO Framework

Macromolecular Materials and Engineering, Volume 311, Issue 5, May 2026.
Classical empirical models fail to predict the dynamic in vivo behavior of chitosan‐alginate nanocarriers. Bridging this translational gap, the novel D‐PARMO framework replaces purely descriptive curve‐fitting with a mechanistically informed operational model.
Parastoo Rekab, Akeem Adeyemi Oladipo
wiley   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Rethinking Extracellular Vesicle Signaling

Advanced Materials, Volume 38, Issue 20, 7 April 2026.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Dietary Probiotics Improve Growth, Immunity and Disease Resistance in Fish Against Aeromonas hydrophila Infection

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
Probiotics offer a promising alternative to antibiotics for managing Aeromonas hydrophila infections in aquaculture. Dietary supplementation of probiotics increases fish health, growth performance, and immune responses, while reducing antibiotic reliance in fish farming.
Md. Ridwanul Islam, Md. Adnan Sajib, Nurunnahar Nadira, Alokesh Kumar Ghosh   +3 more
wiley   +1 more source

Current Overview and Main Challenges of the Use of Galleria mellonella in Biomedical Research

Current Protocols, Volume 6, Issue 4, April 2026.
Abstract Larvae of the greater wax moth Galleria mellonella have become an increasingly important in vivo model for biomedical research, providing a practical, ethical, and biologically relevant alternative to vertebrate organisms. Its suitability as a model system lies in its low maintenance cost, ease of handling, and ability to survive at both ...
Fabiana Alves de Souza Silva, Maria Eduarda da Silva Costa, Patrícia Michelle Nagai de Lima, Jaqueline Lemes Ribeiro, Betina Sayeg Burd, Rondinelli Donizetti Herculano, Laura Beatriz Borim da Silva, Paulo Henrique Fonseca Carmo, Luis Augusto de Almeida‐Silva, Kevin Kavanagh, Juliana Campos Junqueira, Maíra Terra Garcia   +11 more
wiley   +1 more source

Pilus distribution among lineages of group b streptococcus: an evolutionary and clinical perspective [PDF]

, 2014
<b>Background</b><p></p> Group B Streptococcus (GBS) is an opportunistic pathogen in both humans and bovines. Epidemiological and phylogenetic analyses have found strains belonging to certain phylogenetic lineages to be more ...
Davies, H Dele, Lacher, David W, Manning, Shannon D, Singh, Pallavi, Springman, Amber Cody, Waymire, Emily A, Wengert, Samantha L, Zadoks, Ruth N   +7 more
core   +1 more source

The antibody-peptide fusion protein, AT-02, is an effective opsonin with pan-amyloid reactivity

npj Drug Discovery
Abstract In systemic amyloidosis, the progressive accumulation of amyloid fibrils along with extracellular matrix components causes organ dysfunction, reduced quality of life, and is often fatal. Currently, twenty different proteins have been identified in systemic amyloid fibrils.
J. S. Wall, A. D. Williams, M. Balachandran, T. J. Hancock, T. Richey, A. C. Stuckey, S. Macy, C. Wooliver, E. B. Martin, J. W. Jackson, R. E. Heidel, S. Guthrie, M. L. Klein, N. Angell, S. J. Kennel, J. S. Foster   +15 more
openaire   +1 more source

A C3(H20) recycling pathway is a component of the intracellular complement system [PDF]

, 2017
An intracellular complement system (ICS) has recently been described in immune and nonimmune human cells. This system can be activated in a convertase-independent manner from intracellular stores of the complement component C3. The source of these stores
Botto, Bu, Hrishikesh S. Kulkarni, John P. Atkinson, Liszewski, M. Kathryn Liszewski, Michelle Elvington, Nickells, Paula Bertram, Seya, Singer, Vĕtvicka   +11 more
core   +2 more sources

Systemic Inflammation Modulates Clearance and Drives Extra‐Hepatic Distribution of Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) are promising vehicles for targeted therapeutic delivery, capable of encapsulating and transporting biomolecules to specific cells and tissues. Given that inflammation is central to many acute and chronic diseases, understanding EV biodistribution under inflammatory conditions is essential for therapeutic ...
Svetlana Pavlova, Doste R. Mamand, André Görgens, Antje M. Zickler, Wenyi Zheng, Xiuming Liang, Oscar P. B. Wiklander, Manuchehr Abedi‐Valugerdi, Elien Van Wonterghem, Junhua Xie, Zheyu Niu, Samantha Roudi, Dongnan Yan, Ruhani Makkar, Guannan Zhou, Koshi Imami, Matthew J. A Wood, Roosmarijn E. Vandenbroucke, Dhanu Gupta, Samir El Andaloussi   +19 more
wiley   +1 more source