Results 221 to 230 of about 82,984,775 (304)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Hallucination-aware learning and latency optimization transformer (HALL-OPT) for real-time edge intelligence. [PDF]

Sci Rep
Algawiaz D.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Effect of Exchange-Correlation Functionals on Schottky Barriers at Si/Metal Interfaces. [PDF]

J Phys Chem C Nanomater Interfaces
Dovale-Farelo V, Choudhary K.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Erratum: Wavenumber-space wavefront sensorless adaptive-optics for optical coherence tomography: publisher's note. [PDF]

Biomed Opt Express
Ruiz-Lopera S, Veysset D, Bouma BE, Uribe-Patarroyo N.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Parent and practitioner experiences of opt-out consent in neonatal intensive care: a mixed methods study within a trial. [PDF]

Arch Dis Child Fetal Neonatal Ed
Mitchell T, Andrzejewska I, Battersby C, Cole C, Daskalopoulou Z, Dorling J, Gale C, Graham M, Hubbard M, Hardy P, Hurd M, King AR, Manley BJ, Murray D, Nuthall E, O'Connor H, Ojha S, Roberts CT, Rodriquez A, Roehr CC, Stanbury K, Tume L, Young L, Woolfall K.   +23 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Erratum: Learning to simulate realistic human diffuse reflectance spectra (Erratum). [PDF]

J Biomed Opt
Hübner M, Bin Qasim A, Studier-Fischer A, Rees M, Tran Ba V, Nölke JH, Seidlitz S, Sellner J, Heinecke J, Brandt J, Özdemir B, Dreher K, Seitel A, Nickel F, Max Haney C, Kowalewski KF, Ayala L, Maier-Hein L.   +17 more
europepmc   +1 more source