Results 31 to 40 of about 354,465 (294)
Gray matter atrophy rate as a marker of disease progression in AD [PDF]
, 2010 Global gray matter (GM) atrophy rates were quantified from magnetic resonance imaging (MRI) over 6- and 12-month intervals in 37 patients with Alzheimer's disease (AD) and 19 controls using: (1) nonlinear registration and integration of Jacobian values ...
Miller, David H. +29 more
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Progressive auditory neuropathy in patients with Leber's hereditary optic neuropathy [PDF]
, 2004 Objective: To investigate auditory neural involvement in patients with Leber's hereditary optic neuropathy (LHON).Methods: Auditory assessment was undertaken in two patients with LHON.
Luxon, LM, Ceranic, B
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Orphan disease: Cherubism, optic atrophy, and short stature
Indian Journal of Radiology and Imaging, 2018 A 12-year-old female presented with complaints of progressive visual impairment in both her eyes. On clinical examination, she was short for her age and her ophthalmoscopic examination revealed bilateral optic atrophy.
Balaji Jeevanandham +4 more
doaj +1 more source
Interdisciplinary Neurosurgery, 2020 Background: To date, the etiology of optic nerve sheath calcifications is unclear and visual loss secondary to optic nerve sheath calcifications has been reported infrequently.
Patrick K. Jowdy +2 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The contribution of brain reorganisation to recovery in patients with optic neuritis [PDF]
, 2010 In this thesis, the mechanisms of damage and repair in clinically isolated optic neuritis (ON) were investigated in vivo, by combining magnetic resonance imaging (MRI), electrophysiology and optical coherence tomography (OCT).
Jenkins, T.M.
core
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Bilateral optic atrophy in snake envenomation – A case report
Journal of Dr. NTR University of Health Sciences, 2019 Ocular complications following snake bite are usually rare. Snake bite accounts for 4% of all ophthalmoplegias. Optic neuritis and optic atrophy following snake bite have been reported in very few cases.
Ravala Siddeswari +3 more
doaj +1 more source