Results 141 to 150 of about 90,641 (320)
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Ivermectin for onchocercal eye disease (river blindness).
, 2012 BACKGROUND: It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are ...
Ejere, Henry OD +3 more
core +1 more source
Journal of Ophthalmology, 2016 Purpose. To present the safety and effect of endoscopic transethmosphenoid optic canal decompression (ETOCD) for indirect traumatic optic neuropathy (ITON) patients with no-light-perception (NLP). Methods.
Bo Yu, Yingjie Ma, Yunhai Tu, Wencan Wu
doaj +1 more source
Protective Effect of Optic Atrophy 1 on Cardiomyocyte Oxidative Stress: Roles of Mitophagy, Mitochondrial Fission, and MAPK/ERK Signaling. [PDF]
Oxid Med Cell Longev, 2021 Wang Y, Han Z, Xu Z, Zhang J.
europepmc +1 more source
Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes. [PDF]
, 2016 PurposeThe purpose of this study was to compare retinal nerve fiber layer (RNFL) thickness and optical coherence tomography angiography (OCT-A) retinal vasculature measurements in healthy, glaucoma suspect, and glaucoma patients.MethodsTwo hundred sixty ...
Belghith, Akram +11 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
A Rare Clinical Portrait: Unveiling the Complexities of Foster-Kennedy Syndrome
JKS (Jurnal Kedokteran Syiah Kuala)Introduction: Foster-Kennedy Syndrome (FKS) is an uncommon neuro-ophthalmological disorder characterized by unilateral blindness linked with an intracranial tumor. Its defining features, such as unilateral optic disc atrophy and contralateral papilledema,
Putri Nabillah Mulya +2 more
doaj +1 more source
Antisense oligonucleotide therapy for splicing defects in
Acta Ophthalmologica, 2017 SummaryMutations in OPA1 are the main cause of dominant optic atrophy (DOA) and have also been implicated in a variety of syndromic neuropathies such as DOAplus or Behr‐like syndrome. We have recently discovered a disease‐causing deep intronic mutation (DIM) in OPA1 that induces a constitutive inclusion of a cryptic exon into OPA1 transcripts.
B. Wissinger +3 more
openaire +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source