Peripapillary choroidal neovascularization associated with melanocytoma of the optic disc: a clinicopathologic case report [PDF]
, 2018 Background: Melanocytoma of the optic disc is a benign melanocytic tumor that rarely causes visual impairment. We report a case of a melanocytoma of the optic disc with a decreased vision related to a peripapillary choroidal neovascular membrane (PCNVM ...
Bovey, Etienne +3 more
core
A GPU-based Evolution Strategy for Optic Disk Detection in Retinal Images [PDF]
, 2016 La ejecución paralela de aplicaciones usando unidades de procesamiento gráfico (gpu) ha ganado gran interés en la comunidad académica en los años recientes.
González-Calederón, Guillermo +1 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Deep learning-based optic disc classification is affected by optic-disc tilt
Scientific ReportsWe aimed to determine the effect of optic disc tilt on deep learning-based optic disc classification. A total of 2507 fundus photographs were acquired from 2236 eyes of 1809 subjects (mean age of 46 years; 53% men).
Youngwoo Nam +17 more
doaj +1 more source
Optic Disc Identification Methods for Retinal Images [PDF]
Computer Science Journal of Moldova, 2014 Presented are the methods proposed by authors to identify and model the optic disc in colour retinal images. The first three our approaches localized the optic disc in two steps: a) in the green component of RGB image the optic disc area is detected ...
Florin Rotaru +4 more
doaj
Optic disc and cup segmentation for glaucoma detection using Attention U-Net incorporating residual mechanism [PDF]
PeerJ Computer ScienceGlaucoma is a common eye disease that can cause blindness. Accurate detection of the optic disc and cup disc is crucial for glaucoma diagnosis. Algorithm models based on artificial intelligence can assist doctors in improving detection performance.
Yuanyuan Chen, Yongpeng Bai, Yifan Zhang
doaj +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
GMS Ophthalmology Cases, 2014 [english] Importance: Radial optic neurotomy (RON) was first described by Opremcak as a treatment for patients with central retinal vein occlusion (CRVO).
Pinxten, Isabel, Stalmans, Peter
doaj +1 more source
Vertical Macular Asymmetry Measures Derived From SD-OCT for Detection of Early Glaucoma. [PDF]
, 2017 PurposeTo test the hypothesis that vertical asymmetry in macular ganglion cell/inner plexiform layer (GCIPL) thickness can improve detection of early glaucoma.MethodsSixty-nine normal eyes and 101 glaucoma eyes had macular imaging with spectral-domain ...
Afifi, Abdelmonem A +7 more
core +1 more source