Results 31 to 40 of about 1,987 (238)
Optic Disc Pit with An Atypical Presentation
Optic Disc Pit (ODP) results from an imperfect closure of the superior edge of the embryonic fissure, usually associated with macular serous detachment.
Neha Arora, Aniket Patel
doaj +1 more source
Cilioretinal Arteries in Conjunction with a Pit of the Optic Disc
Cilioretinal arteries were noted to accompany pits of the optic disc in 16 of 25 cases (64%). Fourteen of the 16 cases were found to have 2 cilioretinal arteries (86%). The cilioretinal arteries were directly related to the pit of the disc and emerged either from the bottom or the margin of the pit in a proportion of 86%.
Theodossiadis, G.P. +2 more
openaire +3 more sources
Introduction: Optic disk pit (ODP) is a rare congenital abnormality of the optic nerve head. It can be complicated by a macular detachment associated with progressive visual loss. Serous maculopathy can occur in 25-75% of OPD. Methods: Case report Results: 11 years old girl with a complaint of right eye blurred vision was referred to our clinic.
Balčiūnienė, Vilma Jūratė +3 more
openaire +4 more sources
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Occult optic disc pit with macular schisis [PDF]
Sir, We would like to thank Dr Shukla for his comments related to our recent case report relating to a child with an outer retinal layer anomaly at the fovea.1 Shukla claims that we were incorrect to classify this as a full-thickness macula hole.
J C, Park, K N, Frimpong-Ansah
openaire +2 more sources
Introduction. Optic disk pit has been considered as coloboma located, as a rule, near temporal part of the optic disc. Central serous retinal detachment develops in 50 % of patients.
I.I. Shevchenko
doaj +1 more source
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
The first description of congenital optic disc PIT (ODP) was in 1882 by Wiethe who notes a dark depression in both optic discs of a 62-year-old woman (Wiethe 1882). There is no difference between gender, 85% of the patients have unilateral commitment, and the estimated incidence is 1 in 11,000 eyes (Brown et al. 1980; Kelkar et al. 2012).
Mayara Fernanda Pacovska +1 more
openaire +2 more sources

