Results 41 to 50 of about 541,630 (266)

Optic Disc Pit Maculopathy: A Review

Asia-Pacific Journal of Ophthalmology, 2019
Optic disc pit (ODP) is a rare congenital anomaly of the optic disc that can be associated with maculopathy leading to progressive visual deterioration. The vast majority of cases are sporadic and no obvious factors have been correlated with the development of maculopathy.
Dimitrios, Kalogeropoulos, Soon Wai, Ch'ng, Rynn, Lee, Ibrahim, Elaraoud, Maninee, Purohit, Vinaya, Felicida, Magie, Mathew, Naduviledeth, Ajith-Kumar, Ash, Sharma, Arijit, Mitra   +9 more
openaire   +2 more sources

Optic Disc Pit with An Atypical Presentation

Delhi Journal of Ophthalmology, 2018
Optic Disc Pit (ODP) results from an imperfect closure of the superior edge of the embryonic fissure, usually associated with macular serous detachment.
Neha Arora, Aniket Patel
doaj   +1 more source

Cilioretinal Arteries in Conjunction with a Pit of the Optic Disc

Ophthalmologica, 2010
Cilioretinal arteries were noted to accompany pits of the optic disc in 16 of 25 cases (64%). Fourteen of the 16 cases were found to have 2 cilioretinal arteries (86%). The cilioretinal arteries were directly related to the pit of the disc and emerged either from the bottom or the margin of the pit in a proportion of 86%.
Theodossiadis, G.P., Kollia, A.K., Theodossiadis, P.G.   +2 more
openaire   +3 more sources

Optic disc pit maculopathy

Acta Ophthalmologica, 2019
Introduction: Optic disk pit (ODP) is a rare congenital abnormality of the optic nerve head. It can be complicated by a macular detachment associated with progressive visual loss. Serous maculopathy can occur in 25-75% of OPD. Methods: Case report Results: 11 years old girl with a complaint of right eye blurred vision was referred to our clinic.
Balčiūnienė, Vilma Jūratė, Kisil, Tatjana, Gelžinis, Arvydas, Žemaitienė, Reda   +3 more
openaire   +4 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Occult optic disc pit with macular schisis [PDF]

Eye, 2013
Sir, We would like to thank Dr Shukla for his comments related to our recent case report relating to a child with an outer retinal layer anomaly at the fovea.1 Shukla claims that we were incorrect to classify this as a full-thickness macula hole.
J C, Park, K N, Frimpong-Ansah
openaire   +2 more sources

A case of successful laser coagulation in pediatric ophthalmology: a patient with the optic disc pit complicated by serous neuroepithelial detachment

Journal of Ophthalmology, 2016
Introduction. Optic disk pit has been considered as coloboma located, as a rule, near temporal part of the optic disc. Central serous retinal detachment develops in 50 % of patients.
I.I. Shevchenko
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source