Results 31 to 40 of about 1,825 (178)

Semaglutide and non‐arteritic anterior ischaemic optic neuropathy: Review and interpretation of reported association

Acta Ophthalmologica, EarlyView.
Abstract This review covers a seminal study of the relation between exposure to the glucagon‐like peptide 1 (GLP‐1) agonist semaglutide and incident non‐arteritic anterior ischaemic optic neuropathy (NAION) in a neuro‐ophthalmology clinic setting, subsequent studies in unselected populations, a meta‐analysis of clinical trials and pathophysiology ...
Abdullah Amini, Steffen Hamann, Michael Larsen   +2 more
wiley   +1 more source

Young Adults With Anterior Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen Study. [PDF]

, 2020
PURPOSE: Optic disc drusen (ODD), present in 2% of the general population, have occasionally been reported in patients with nonarteritic anterior ischemic optic neuropathy (NA-AION). The purpose of this study was to examine the prevalence of ODD in young
Biousse, V, Bursztyn, L, Citirak, G, Costello, F, Crum, AV, Digre, K, Fard, MA, Fraser, CL, Fraser, JA, Hamann, S, Huna-Baron, R, Katz, B, Lawlor, M, Malmqvist, L, Newman, NJ, Optic Disc Drusen Studies Consortium, Peragallo, JH, Petzold, A, Sibony, PA, Subramanian, PS, Warner, JEA, Wegener, M, Wong, SH   +22 more
core  

Comparison of treatment routine using aflibercept: Strict vs. relaxed retreatment regimen (TOLERANT study)—A non‐inferiority, randomized controlled trial

Acta Ophthalmologica, EarlyView.
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi, Lieselotte E. Berger, Sandrine Zweifel, Matthias D. Becker, Stephan Michels, Odile Stalder, Joel‐Benjamin Lincke, Oussama Habra, Sebastian Wolf, Martin S. Zinkernagel   +9 more
wiley   +1 more source

Enhanced Depth Imaging Optical Coherence Tomography of Optic Nerve Head Drusen: A Comparison of Cases with and without Visual Field Loss [PDF]

, 2017
PURPOSE: Enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD OCT) has been recognized as the most sensitive tool to diagnose optic nerve head drusen (ONHD).
Keane, PA, Plant, GT, Sabah, M, Traber, GL, Weber, KP   +4 more
core  

Correlation of Structure With Function: Future Utilities for Optical Coherence Tomography Angiography in Neuro‐Ophthalmology

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani, Sudha Cugati, Celia Chen   +2 more
wiley   +1 more source

Optic nerve sonography in the diagnostic evaluation of pseudopapilledema and raised intracranial pressure: A cross-sectional study [PDF]

, 2015
Introduction. Differentiating pseudopapilledema from papilledema which is optic disk edema and a result of increased ICP (intracranial pressure) is important and can be done with noninvasive methods like orbital ultrasound examination. Method. This was a
Abdollahi, S., Esmaeeli, S., Mehrpour, M., Oliaee Torshizi, F., Taghipour, S.   +4 more
core   +3 more sources

N‐terminomics and proteomics analysis of Calpain‐2 reveal key proteolytic processing of metabolic and cell adhesion proteins

Protein Science, Volume 34, Issue 5, May 2025.
Abstract Aberrant levels of the cysteine protease Calpain‐2 have been linked to neurodegeneration, inflammation, and cancer, yet our understanding of this protease and its substrates remains limited. Systematic studies to identify Calpain‐2 substrates have been largely confined to peptide libraries or in vitro studies, which fail to represent ...
Anjali Kapilan, Mitchell Bulluss, Alexander R. Ziegler, Mohamed Dabaja, Afshin Derakhshani, Anthonia Anowai, Victoria Armstrong, Rhiannon Campden, Daniel Young, Young Joo Sun, Nichollas E. Scott, Laura E. Edgington‐Mitchell, Vinit B. Mahajan, Antoine Dufour   +13 more
wiley   +1 more source

Bilateral Optic Disc Drusen with Neuroretinitis [PDF]

, 2022
Background: Neuroretinitis is an inflammation of the posterior pole of the eye, resulting in optic disc edema and macular star formation. Systemic conditions associated with these findings include tuberculosis, toxoplasmosis, syphilis, lyme disease ...
Kreinbrink, Jessica, OD, Weibel, Andrew, OD, Weibel, Katherine, OD   +2 more
core   +1 more source

Peripapillary choroidal vascularity of paediatric myopic eyes with peripapillary hyperreflective ovoid mass‐like structures

Acta Ophthalmologica, Volume 103, Issue 2, Page e94-e103, March 2025.
Abstract Purpose To assess the peripapillary choroidal vasculature in paediatric myopic patients with and without peripapillary hyperreflective ovoid mass‐like structures (PHOMS). Methods This prospective study includes 60 eyes of 60 myopic (spherical equivalent [SE] <−1.00 dioptre [D]) patients with (n = 30) and without (n = 30) PHOMS (PHOMS [+] and ...
Furkan Kirik, Didem Dizdar Yiğit, Mehmet Orkun Sevik, Kamile Melis Ertürk, Farid İskandarov, Özlem Şahin, Hakan Özdemir   +6 more
wiley   +1 more source

Crowded Disc in a High Hyperopic Patient Misdiagnosed as Papilledema [PDF]

, 2019
A 16 year old female was referred to neurological clinic with diagnosis of papilledema for neurological evaluation. After consultation with us we became suspicious of pseudopapilledema according to refraction and biometric characteristics of the eye and ...
Attarian, Behnoosh, Firoozian, Nina, Nourizade , Parivash, Yadgari, Maryam   +3 more
core   +2 more sources