Results 31 to 40 of about 424,514 (174)
Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1420-1435, July 2026.Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde +9 more
wiley +1 more source
Acute visual loss in a patient with optic disc drusen
, 2013 Deborah KL Tan,1,2 Sharon LC Tow1–3 1Singapore National Eye Centre, 2Singapore Eye Research Institute, 3National University Health System, Singapore Abstract: Here we report a case of sudden, unilateral, painless visual loss in a middle-aged ...
Tow SL, Tan DK
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Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy
Aging Cell, Volume 25, Issue 7, July 2026.Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang +7 more
wiley +1 more source
Nanophthalmos–retinitis pigmentosa–foveoschisis–optic disk drusen syndrome in an Indian patient
Indian Journal of Ophthalmology. Case Reports, 2023 Abhilasha Baharani +1 more
doaj +1 more source
, 2016 Optic disc drusen are abnormal deposits of protein-like material in the optic disc - the front part of the optic ...
North American Neuro-Ophthalmology Society
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Evaluation of Peripapillary and Macular Vascular Flow Changes with OCT-A in Patients with Superficial Optic Disk Drusen. [PDF]
Sisli Etfal Hastan Tip Bul, 2022 Turker IC +6 more
europepmc +1 more source
, 2008 Optic disc drusen are abnormal deposits of protein-like material in the optic disc - the front part of the optic ...
NANOS
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Optic Disc Drusen in Patients With Ocular Hypertension: A Case Series and Review of the Literature. [PDF]
J Neuroophthalmol, 2022 Kohli D +4 more
europepmc +1 more source
, 2008 Optic disc drusen are abnormal deposits of protein-like material in the optic disc - the front part of the optic ...
NANOS
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Visible Optic Disc Drusen in a Children
, 2021 Optic disc drusen are acellular deposits located in the head of the optic nerve that increase in size and become calcified over time. Drusen tend to buried in early life and become superficial and visible later in childhood, at an average age of 10-12 ...
Emely Karam; Andrea Cabrera; Andres Castaño
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