Results 71 to 80 of about 86,920 (253)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The role of optic flow on reactive brain processing in cognitive tasks during locomotion

Brain Research Bulletin
Perception and action share neural resources that must be flexibly allocated across simultaneous tasks. In this context, the optic flow provides key visual input during locomotion and may interact with concurrent cognitive processing. This study aimed to:
BiancaMaria Di Bello, Natalie Ferrulli, Camilla Panacci, Margherita Filosa, Sabrina Pitzalis, Francesco Di Russo   +5 more
doaj   +1 more source

A Bio-inspired Collision Avoidance Model Based on Spatial Information Derived from Motion Detectors Leads to Common Routes. [PDF]

PLoS Computational Biology, 2015
Avoiding collisions is one of the most basic needs of any mobile agent, both biological and technical, when searching around or aiming toward a goal.
Olivier J N Bertrand, Jens P Lindemann, Martin Egelhaaf   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Shape of a Vehicle Windshield Affects Reaction Time and Brain Activity During a Target Detection Task

Frontiers in Human Neuroscience, 2020
Background: Achieving clear visibility through a windshield is one of the crucial factors in manufacturing a safe and comfortable vehicle. The optic flow (OF) through the windshield has been reported to divert attention and could impair visibility ...
Takafumi Sasaoka, Maro G. Machizawa, Yoshihisa Okamoto, Koji Iwase, Toshihiro Yoshida, Nanae Michida, Atsuhide Kishi, Masaki Chiba, Kazuo Nishikawa, Shigeto Yamawaki, Takahide Nouzawa   +10 more
doaj   +1 more source

On discontinuous optical flow

Comput. Artif. Intell., 2000
This paper deals with an analysis of image motion in frequency space with respect to motion discontinuities and surface translucence. The frequency structure of motion discontinuities due to occlusion is derived under models of constant and linear optical flow. Authors demonstrate its various geometrical properties.
Beauchemin, S. S., Barron, J. L.
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Integration of parallel pathways for flight control in a hawkmoth reflects prevalence and relevance of natural visual cues

eLife
An animal’s behaviour is the result of multiple neural pathways acting in parallel, receiving information across and within sensory modalities at the same time. How these pathways are integrated, particularly when their individual outputs are in conflict,
Ronja Bigge, Rebecca Grittner, Anna Lisa Stöckl   +2 more
doaj   +1 more source

Using Optic Flow for the Estimation of Travel Distance

i-Perception, 2011
Much research on optic flow has been concerned with the estimation of heading and the control of the direction of self-motion. In my presentation I will instead focus on a different use of optic flow, namely the estimation of the distance that one has ...
Markus Lappe
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source