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Oxidative Stress: A Suitable Therapeutic Target for Optic Nerve Diseases? [PDF]

open access: goldAntioxidants, 2023
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve.
Francesco Buonfiglio   +3 more
doaj   +4 more sources

Applications of Optical Coherence Tomography in Optic Nerve Head Diseases: A Narrative Review [PDF]

open access: yesDiagnostics
Optical coherence tomography (OCT) is a non-invasive imaging tool that is currently used in the evaluation and management of neuro-ophthalmic disorders. The detailed ability to visualize the optic nerve head, peripapillary retinal nerve fiber layer, and ...
Mohamed M. Khodeiry   +4 more
doaj   +2 more sources

Optical coherence tomography angiography of the optic disc; an overview [PDF]

open access: yesJournal of Ophthalmic & Vision Research, 2017
Different diseases of the optic disc may be caused by or lead to abnormal vasculature at the optic nerve head. Optical coherence tomography angiography (OCTA) is a novel technology that provides high resolution mapping of the retinal and optic disc ...
Handan Akil   +3 more
doaj   +9 more sources

Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases [PDF]

open access: goldJournal of Ophthalmology, 2012
The photopic negative response (PhNR) in response to a brief flash is a negative-going wave following the b-wave of the cone electroretinogram (ERG) that is driven by retinal ganglion cells (RGCs).
Shigeki Machida
doaj   +2 more sources

Auditory evoked phosphenes in optic nerve disease [PDF]

open access: bronzeJournal of Neurology, Neurosurgery & Psychiatry, 1982
Five patients with optic neuropathy, four vascular and one demyelinating, are described who each complained of an unusual symptom. Bright flashes of light (phosphenes) occurred in the affected eyes and were evoked by sudden unexpected sounds. Movement of the eye alone did not reproduce the symptom.
Nathan Page   +2 more
openalex   +4 more sources

Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials. [PDF]

open access: hybridWorld J Stem Cells, 2016
Labrador-Velandia S   +7 more
europepmc   +3 more sources

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

open access: yesBrain Sciences, 2023
Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng   +4 more
doaj   +1 more source

Behaviour of Disc Oedema During and After Amiodarone Optic Neuropathy: Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
A 73-year-old woman with atrial fibrillation treated with Amiodarone presented with Optic Disc oedema in right eye (OD). Using Optical Coherence Tomography (OCT) we describe the impact of this neuropathy on Retinal Nerve Fibre Layer (RNFL). At diagnosis
Med. Alejandro Martínez-López-Portillo   +4 more
doaj   +1 more source

The Role of Electrical Stimulation in Management of Retinal and Optic Nerve Degenerative and Dystrophic Disorders. Literature Review

open access: yesOftalʹmologiâ, 2021
This article presents actual data on the retinal and optic nerve electrical stimulation. The physical basics of the electrical stimulation biological effect on cellular elements and nerve fibers are discussed.
L. S. Pateyuk   +3 more
doaj   +1 more source

Glymphatic imaging and modulation of the optic nerve

open access: yesNeural Regeneration Research, 2022
Optic nerve health is essential for proper function of the visual system. However, the pathophysiology of certain neurodegenerative disease processes affecting the optic nerve, such as glaucoma, is not fully understood. Recently, it was hypothesized that
Anisha Kasi   +3 more
doaj   +1 more source

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