Results 1 to 10 of about 253,994 (316)

Gene therapy for optic nerve disease [PDF]

open access: bronzeEye, 2004
There has been recent interest in the potential use of gene therapy techniques to treat ocular disease. In this article, we consider the optic nerve diseases that are potentially most amenable to gene therapy.We discuss the recent success of gene transfer experiments in animal models of glaucoma, optic neuritis, Leber's hereditary optic neuropathy ...
Keith R Martin, Harry A. Quigley
openaire   +4 more sources

Vitreous fluorophotometry in optic nerve disease. [PDF]

open access: bronzeBritish Journal of Ophthalmology, 1982
Posterior vitreous fluorophotometry measurements have been shown to be increased in patients with acute retrobulbar neuritis. We studied 12 patients who had optic neuropathy by posterior vitreous fluorophotometry, with and without correction for blood fluorescein concentration.
L S Braude, José Cunha-Vaz, M Frenkel
openaire   +5 more sources

A history of the optic nerve and its diseases [PDF]

open access: bronzeEye, 2004
We will trace the history of ideas about optic nerve anatomy and function in the Western world from the ancient Greeks to the early 20th century and show how these influenced causal theories of optic nerve diseases. Greek and Roman humoral physiology needed a hollow optic nerve, the obstruction of which prevented the flow of visual spirit to and from ...
David Taylor, Carole Reeves
openaire   +4 more sources

Image analysis of optic nerve disease [PDF]

open access: bronzeEye, 2004
Existing methodologies for imaging the optic nerve head surface topography and measuring the retinal nerve fibre layer thickness include confocal scanning laser ophthalmoscopy (Heidelberg retinal tomograph), optical coherence tomography, and scanning laser polarimetry.
Claude F. Burgoyne
openaire   +3 more sources

Oxidative Stress: A Suitable Therapeutic Target for Optic Nerve Diseases? [PDF]

open access: yesAntioxidants (Basel), 2023
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve.
Buonfiglio F   +3 more
europepmc   +2 more sources

Auditory evoked phosphenes in optic nerve disease [PDF]

open access: bronzeJournal of Neurology, Neurosurgery & Psychiatry, 1982
Five patients with optic neuropathy, four vascular and one demyelinating, are described who each complained of an unusual symptom. Bright flashes of light (phosphenes) occurred in the affected eyes and were evoked by sudden unexpected sounds. Movement of the eye alone did not reproduce the symptom.
Ngr Page, Sanders, JP Bolger
openaire   +4 more sources

Retinal and Optic Nerve Diseases

open access: yesVeterinary Clinics of North America: Equine Practice, 1992
Basic knowledge of the normal appearance and variations of the equine fundus coupled with frequent practice in ophthalmology will allow equine practitioners to be confident when assessing the equine fundus during ophthalmic examinations. Once the normal variations are mastered, appreciation of retinal, choroidal, optic nerve, and vitreal abnormalities ...
openaire   +3 more sources

Electrophysiological assessment of optic nerve disease [PDF]

open access: yesEye, 2004
The electrophysiological findings in optic nerve and primary ganglion cell dysfunction are reviewed. The value of the pattern reversal visual-evoked potential (VEP) in the diagnosis of optic nerve disease, and the pattern appearance VEP in the demonstration of the intracranial misrouting associated with albinism, are discussed.
openaire   +3 more sources

THE OCCURRENCE OF OPTIC NERVE ATROPHY IN GENERAL DISEASE. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1896
The origin of most cases of optic nerve atrophy is certainly obscure. There can be no doubt, when the amblyopia and characteristic disk changes follow traumatism, peripheral disease, or there is positive diagnosis of cerebral disease, or following the continued action of some virus or poison in the system, that is known to affect the optic nerve.
openaire   +3 more sources

Home - About - Disclaimer - Privacy