Glaucoma is a group of diseases commonly defined by an increased intraocular pressure (IOP) which interferes with normal function of the optic nerve and retina.
Andreea A. Zăvoi, Andra Elena Enache
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Introduction: Optic neuropathies are a broad group of diseases in which the dominant disturbance is damage to the optic nerve, often irreversible. Underlying causes of neuropathy are both genetic and environmental.
Joanna Kobak +6 more
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Morning Glory Disc Anomaly, A Report of a Successfully Treated Case of Functional Amblyopia [PDF]
Morning Glory Disc Anomaly (MGDA) is a congenital malformation of the optic nerve characterized by the presence of a funnel-shaped macropapilla with neuroglial remnants in its center surrounded by an elevated and pigmented chorioretinal ring.
Humberto Cavazos-Adame +3 more
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Photopic negative response recorded with RETeval system in eyes with optic nerve disorders
Electroretinography (ERG) is used to evaluate the physiological status of the retina and optic nerve. The purpose of this study was to determine the usefulness of ERGs recorded with the RETeval system in diagnosing optic nerve diseases.
Tsutomu Yamashita +7 more
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Gene therapy for optic nerve disease [PDF]
There has been recent interest in the potential use of gene therapy techniques to treat ocular disease. In this article, we consider the optic nerve diseases that are potentially most amenable to gene therapy.We discuss the recent success of gene transfer experiments in animal models of glaucoma, optic neuritis, Leber's hereditary optic neuropathy ...
K R G, Martin, H A, Quigley
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Medical management of hereditary optic neuropathies. [PDF]
Hereditary optic neuropathies are diseases affecting the optic nerve. The most common are mitochondrial hereditary optic neuropathies, i.e., the maternally inherited Leber's hereditary optic neuropathy (LHON) and dominant optic atrophy (DOA).
Barboni, Piero +4 more
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Glaucoma and cigarette smoking: a review of narrative reviews [PDF]
Background: Glaucoma is an optic neuropathy associated with visual field changes for which high intra-ocular pressure is a major risk factor. Emerging research indicates that modifiable factors, among which the cigarette smoke, besides IOP may be ...
DI MURRO, FRANCESCA +3 more
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α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies
There is increasing interest in studying retinal biomarkers for various neurodegenerative diseases. Specific protein aggregates associated with neurodegenerative diseases are present in the retina and could be visualised in a non-invasive way. This study
Frederique J. Hart de Ruyter +10 more
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Optic nerve sheath diameter ultrasound evaluation in intensive care unit. possible role and clinical aspects in neurological critical patients' daily monitoring [PDF]
Background. The increase of the optic nerve sheath diameter (ONSD) is a reliable, noninvasive sonographic marker of intracranial hypertension. Aim of the study was to demonstrate the efficacy of ONSD evaluation, when monitoring neurocritical patients, to
DI PIERO, Vittorio +6 more
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Prediction of the course of primary open-angle glaucoma in combination with diabetic retinopathy using a mathematical model [PDF]
It is possible to accurately diagnose diseases in the early stages using optical coherence tomography. A mathematical model has been developed for two diseases: glaucoma and diabetic retinopathy.
Vorobyeva I V
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