The Time Course of Gene Expression during Reactive Gliosis in the Optic Nerve. [PDF]
PLoS ONE, 2013 Reactive gliosis is a complex process that involves changes in gene expression and morphological remodeling. The mouse optic nerve, where astrocytes, microglia and oligodendrocytes interact with retinal ganglion cell axons and each other, is a ...
Juan Qu, Tatjana C Jakobs
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Objective Assessment of Visual Field Defects Caused by Optic Chiasm and Its Posterior Visual Pathway Injury [PDF]
Fayixue Zazhi, 2023 Objective To investigate the characteristics and objective assessment method of visual field defects caused by optic chiasm and its posterior visual pathway injury.
Jian XIANG, Xu WANG, Li-li YU, Kang-jia JIN, Ying-kai YANG
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Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases
Brain Sciences, 2023 Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng +4 more
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Cells, 2023 Axonal degeneration resulting from optic nerve damage can lead to the progressive death of retinal ganglion cells (RGCs), culminating in irreversible vision loss.
Hyun-Ah Shin +7 more
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Sheath-Preserving Complete Optic Nerve Avulsion Following Closed-Globe Injury: A Case Report
Türk Oftalmoloji Dergisi, 2022 A 29-year-old man presented with a sudden loss of vision after a closed-globe injury. At presentation, he had no light perception in the right eye and the right pupil was dilated and nonreactive to light.
Seray Şahin +3 more
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Monitoring of optic nerve sheath diameter on computed tomography for noninvasive assessment of intracranial pressure: Case report: Optic nerve sheath and intracranial pressure [PDF]
Serbian Journal of Anesthesia and Intensive Therapy, 2022 Introduction: It is important to measure intracranial pressure because traumatic brain injuries lead to intracranial hypertension and ischaemic brain lesions.
Bojičić Adrijana +4 more
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SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury. [PDF]
PLoS ONE, 2016 Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1)
James D Nicholson +2 more
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Sox10 Expression in Goldfish Retina and Optic Nerve Head in Controls and after the Application of Two Different Lesion Paradigms. [PDF]
PLoS ONE, 2016 The mammalian central nervous system (CNS) is unable to regenerate. In contrast, the CNS of fish, including the visual system, is able to regenerate after damage.
Marta Parrilla +6 more
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CONTUSION INJURIES OF THE OPTIC NERVE [PDF]
Australian and New Zealand Journal of Ophthalmology, 1986 AbstractIndirect trauma to the optic nerve with secondary optic atrophy may result from minor trauma and has traditionally been associated with a poor visual prognosis. The case of a 32‐year‐old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial ...
A M, Brooks, J D, Cairns
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Assessment of optic nerve and optic tract alterations in patients with orbital space-occupying lesions using probabilistic diffusion tractography [PDF]
International Journal of Ophthalmology, 2019 AIM: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography (PDT).
Chun-Nan Wu +6 more
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