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Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

open access: yesBrain Sciences, 2023
Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng   +4 more
doaj   +4 more sources

Sheath-Preserving Complete Optic Nerve Avulsion Following Closed-Globe Injury: A Case Report

open access: yesTürk Oftalmoloji Dergisi, 2022
A 29-year-old man presented with a sudden loss of vision after a closed-globe injury. At presentation, he had no light perception in the right eye and the right pupil was dilated and nonreactive to light.
Seray Şahin   +3 more
doaj   +2 more sources

Objective Assessment of Visual Field Defects Caused by Optic Chiasm and Its Posterior Visual Pathway Injury [PDF]

open access: yesFayixue Zazhi, 2023
Objective To investigate the characteristics and objective assessment method of visual field defects caused by optic chiasm and its posterior visual pathway injury.
Jian XIANG, Xu WANG, Li-li YU, Kang-jia JIN, Ying-kai YANG
doaj   +1 more source

Unveiling Neuroprotection and Regeneration Mechanisms in Optic Nerve Injury: Insight from Neural Progenitor Cell Therapy with Focus on Vps35 and Syntaxin12

open access: yesCells, 2023
Axonal degeneration resulting from optic nerve damage can lead to the progressive death of retinal ganglion cells (RGCs), culminating in irreversible vision loss.
Hyun-Ah Shin   +7 more
doaj   +1 more source

Monitoring of optic nerve sheath diameter on computed tomography for noninvasive assessment of intracranial pressure: Case report: Optic nerve sheath and intracranial pressure [PDF]

open access: yesSerbian Journal of Anesthesia and Intensive Therapy, 2022
Introduction: It is important to measure intracranial pressure because traumatic brain injuries lead to intracranial hypertension and ischaemic brain lesions.
Bojičić Adrijana   +4 more
doaj   +1 more source

SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury. [PDF]

open access: yesPLoS ONE, 2016
Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1)
James D Nicholson   +2 more
doaj   +1 more source

Sox10 Expression in Goldfish Retina and Optic Nerve Head in Controls and after the Application of Two Different Lesion Paradigms. [PDF]

open access: yesPLoS ONE, 2016
The mammalian central nervous system (CNS) is unable to regenerate. In contrast, the CNS of fish, including the visual system, is able to regenerate after damage.
Marta Parrilla   +6 more
doaj   +1 more source

Assessment of optic nerve and optic tract alterations in patients with orbital space-occupying lesions using probabilistic diffusion tractography [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography (PDT).
Chun-Nan Wu   +6 more
doaj   +1 more source

Multimodality Imaging in Mechanical Orbital Trauma

open access: yesDelhi Journal of Ophthalmology, 2022
Orbital trauma is commonly associated with trauma to head and face and the radiologist plays a key role in assessing these injuries. Common forms of orbital injury include bony fractures, anterior chamber injuries, injuries to lens, open-globe injuries ...
A Ebinesh   +3 more
doaj   +1 more source

Therapeutic potential of human umbilical cord–derived mesenchymal stem cells transplantation in rats with optic nerve injury

open access: yesIndian Journal of Ophthalmology, 2022
Purpose: There are no effective treatments currently available for optic nerve transection injuries. Stem cell therapy represents a feasible future treatment option.
Sook Y Looi   +10 more
doaj   +1 more source

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