Results 11 to 20 of about 33,089 (310)
Traumatic Optic Neuropathy and Second Optic Nerve Injuries [PDF]
JAMA Ophthalmology, 2014 Current controversy about the primary treatment of traumatic optic neuropathy (TON) has anchored on final vision following injury, but, to our knowledge, no study has examined the effect of different treatments on regaining and protecting optic nerve reserve or on the outcome of second optic nerve injuries.To assess vision improvement in patients ...
William Marshall, Guy +5 more
openaire +4 more sources
Multimodality Imaging in Mechanical Orbital Trauma
Delhi Journal of Ophthalmology, 2022 Orbital trauma is commonly associated with trauma to head and face and the radiologist plays a key role in assessing these injuries. Common forms of orbital injury include bony fractures, anterior chamber injuries, injuries to lens, open-globe injuries ...
A Ebinesh +3 more
doaj +1 more source
Indian Journal of Ophthalmology, 2022 Purpose: There are no effective treatments currently available for optic nerve transection injuries. Stem cell therapy represents a feasible future treatment option.
Sook Y Looi +10 more
doaj +1 more source
NGF, TrkA-P and neuroprotection after a hypoxic event in the developing central nervous system [PDF]
, 2018 A decrease in the concentration of oxygen in the blood and tissues (hypoxia) produces important, sometimes irreversible, damages in the central nervous system (CNS) both during development and also postnatally.
Bogetti, María Eugenia +4 more
core +1 more source
Retinal Genomic Fabric Remodeling after Optic Nerve Injury [PDF]
Genes, 2021 Glaucoma is a multifactorial neurodegenerative disease, characterized by degeneration of the retinal ganglion cells (RGCs). There has been little progress in developing efficient strategies for neuroprotection in glaucoma. We profiled the retina transcriptome of Lister Hooded rats at 2 weeks after optic nerve crush (ONC) and analyzed the data from the ...
Pedro Henrique Victorino +7 more
openaire +3 more sources
Mass spectrometry dataset of LC-MS lipidomics analysis of Xenopus laevis optic nerve
Data in Brief, 2023 CNS injuries of the anuran amphibian, Xenopus laevis, are uniquely suited for studying the molecular compositions of neuronal regeneration of retinal ganglion cells (RGC) due to a functional recovery of optic axons disparate to adult mammalian analogues.
Emily Neag +5 more
doaj +1 more source
The glia response after peripheral nerve injury: A comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies [PDF]
, 2017 The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). One reason for this difference is the difference in glial cell types between the two systems.
Barton, Matthew J. +4 more
core +2 more sources
Review of a new concept of glaucoma pathogenesis based on the glymphatic theory of cerebrospinal fluid circulation [PDF]
Research Results in Pharmacology, 2020 General aspects of glaucoma: Glaucoma is a heterogeneous multi-factorial disease that is one of the main causes of blindness, along with degeneration of retinal ganglion cells and optic nerve atrophy.
Aleksandr A. Dolzhikov +6 more
doaj +3 more sources
670 nm light mitigates oxygen-induced degeneration in C57BL/6J mouse retina [PDF]
, 2016 BACKGROUND Irradiation with light wavelengths from the far red (FR) to the near infrared (NIR) spectrum (600 nm -1000 nm) has been shown to have beneficial effects in several disease models.
Albarracin, Rizalyn +4 more
core +1 more source
Experimental and Molecular Medicine, 2019 Eye disease: switching signals for repairing injured optic nerves Regulating molecular signaling pathways that control the degradation of cellular components—a process known as autophagy—could offer a new approach to treating optic nerve damage after ...
Yao-Tseng Wen +3 more
doaj +1 more source