Results 11 to 20 of about 16,836 (256)

CONTUSION INJURIES OF THE OPTIC NERVE [PDF]

open access: yesAustralian and New Zealand Journal of Ophthalmology, 1986
AbstractIndirect trauma to the optic nerve with secondary optic atrophy may result from minor trauma and has traditionally been associated with a poor visual prognosis. The case of a 32‐year‐old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial ...
A M Brooks, Anne M V Brooks
exaly   +3 more sources

Traumatic Optic Neuropathy and Second Optic Nerve Injuries [PDF]

open access: yesJAMA Ophthalmology, 2014
Current controversy about the primary treatment of traumatic optic neuropathy (TON) has anchored on final vision following injury, but, to our knowledge, no study has examined the effect of different treatments on regaining and protecting optic nerve reserve or on the outcome of second optic nerve injuries.To assess vision improvement in patients ...
Robert B Parke   +2 more
exaly   +3 more sources

Morphological and functional changes of the optic nerve following traumatic optic nerve injuries in rabbits. [PDF]

open access: yesBiomed Rep, 2016
The aim of the present study was to investigate the morphological changes of the optic nerve following traumatic injuries and decompression at different times after injury, and to observe the changes of the visually evoked potentials, to identify the relevant associations between surgical opportunity and the clinical effect of traumatic optic nerve ...
Xue F   +5 more
europepmc   +4 more sources

Downregulation of BM88 After Optic Nerve Injury

open access: yesInvestigative Opthalmology & Visual Science, 2014
BM88 is a cell-cycle exit and neuronal differentiation protein that has been used as a marker of surviving retinal ganglion cells (RGCs) after optic nerve injury. Thy1.1 has also been used as a marker for RGC loss, but after optic nerve crush (ONC) a decrease in Thy1.1 expression precedes the loss of RGCs.
Alexander Ball   +2 more
exaly   +3 more sources

Response of Retinal Connexin43 to Optic Nerve Injury

open access: yesInvestigative Opthalmology & Visual Science, 2011
To characterize the spatial and temporal expression of Connexin43 (Cx43) after partial optic nerve transection and evaluate its relationship to retinal ganglion cell (RGC) loss and retinal glial response.Partial, unilateral, superior optic nerve transection was performed in 150 Wistar rats. The retinas were evaluated at 8 and 24 hours and 3, 7, 14, 28,
Cameron Johnson   +2 more
exaly   +3 more sources

Objective Assessment of Visual Field Defects Caused by Optic Chiasm and Its Posterior Visual Pathway Injury [PDF]

open access: yesFayixue Zazhi, 2023
Objective To investigate the characteristics and objective assessment method of visual field defects caused by optic chiasm and its posterior visual pathway injury.
Jian XIANG, Xu WANG, Li-li YU, Kang-jia JIN, Ying-kai YANG
doaj   +1 more source

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

open access: yesBrain Sciences, 2023
Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng   +4 more
doaj   +1 more source

Unveiling Neuroprotection and Regeneration Mechanisms in Optic Nerve Injury: Insight from Neural Progenitor Cell Therapy with Focus on Vps35 and Syntaxin12

open access: yesCells, 2023
Axonal degeneration resulting from optic nerve damage can lead to the progressive death of retinal ganglion cells (RGCs), culminating in irreversible vision loss.
Hyun-Ah Shin   +7 more
doaj   +1 more source

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