Results 31 to 40 of about 16,836 (256)

mTORC2 activation protects retinal ganglion cells via Akt signaling after autophagy induction in traumatic optic nerve injury

open access: yesExperimental and Molecular Medicine, 2019
Eye disease: switching signals for repairing injured optic nerves Regulating molecular signaling pathways that control the degradation of cellular components—a process known as autophagy—could offer a new approach to treating optic nerve damage after ...
Yao-Tseng Wen   +3 more
doaj   +1 more source

Knockdown of Porf-2 restores visual function after optic nerve crush injury

open access: yesCell Death and Disease, 2023
Retinal ganglion cells (RGCs), the sole output neurons in the eyes, are vulnerable to diverse insults in many pathological conditions, which can lead to permanent vision dysfunction.
Di Chen   +11 more
doaj   +1 more source

Traumatic chiasmopathy following mild trauma in a patient with thyroid orbitopathy

open access: yesAmerican Journal of Ophthalmology Case Reports, 2021
Purpose: Traumatic injury to the optic chiasm is rare and most frequently caused by high-velocity head trauma. It classically results in bitemporal hemianopsia and often presents in conjunction with multiple other traumatic injuries, such as skull ...
Matthew L. O'Sullivan   +1 more
doaj   +1 more source

ROLE OF TRANSOCULAR ULTRASOUND IN IDENTIFYING RAISED INTRACRANIAL PRESSURE AND PREDICTING INTRACRANIAL BLEED IN TRAUMATIC BRAIN INJURIES

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To know the efficacy of transocular ultrasound (TOU) in identification of elevated intracranial pressure (eICP) and early prediction of intracranial bleed in traumatic brain injuries (TBI). Study Design: Descriptive study.
Muhammad Asim Ghauri   +6 more
doaj   +4 more sources

Traumatic optic neuropathy secondary to acupuncture treatment for glaucoma: A case report

open access: yesJournal of Acute Disease, 2018
Internal organ injuries have been recognized as a major complication of acupuncture. Reported ocular adverse events include traumatic cataract, oculomotor nerve injury, endophthalmitis and retinal puncture.
Wen Yee Lee   +3 more
doaj   +1 more source

A rare case of traumatic globe luxation following a road traffic accident

open access: yesJournal of Clinical Ophthalmology and Research
Traumatic globe luxation is a rare clinical entity. Most of these cases have associated trauma to eyeball, injury to extraocular muscles and optic nerve injuries.
Brajmohan Chaudhary, Versha Sekar
doaj   +1 more source

Strategies to Promote Long-Distance Optic Nerve Regeneration

open access: yesFrontiers in Cellular Neuroscience, 2020
Mammalian retinal ganglion cells (RGCs) in the central nervous system (CNS) often die after optic nerve injury and surviving RGCs fail to regenerate their axons, eventually resulting in irreversible vision loss.
Shu-Guang Yang   +7 more
doaj   +1 more source

Morphofunctional aspects of restorative processes in the optic nerve after traumatic injury under the influence of high doses of corticosteroids

open access: yesJournal of Ophthalmology, 2015
Search of conditions conducive to the activation of regenerative processes and restoration of the functions of the optic nerve after traumatic injuries is relevant.
N.M. Moiseenko
doaj   +1 more source

Expression of inducible heat shock proteins Hsp27 and Hsp70 in the visual pathway of rats subjected to various models of retinal ganglion cell injury. [PDF]

open access: yesPLoS ONE, 2014
Inducible heat shock proteins (Hsps) are upregulated in the central nervous system in response to a wide variety of injuries. Surprisingly, however, no coherent picture has emerged regarding the magnitude, duration and cellular distribution of inducible ...
Glyn Chidlow   +2 more
doaj   +1 more source

Our Experience in Endoscopic Transnasal Optic Nerve Decompression

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery
INTRODUCTION: Traumatic optic neuropathy (TON), a severe complication following head injury, affects about 0.5% to 5% of patients with closed head injuries.1 Visual acuity (VA) loss associated with TON can be partial or complete and temporary or ...
Saravana Selvan Velmurugan   +5 more
doaj   +1 more source

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