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Downregulation of BM88 After Optic Nerve Injury
BM88 is a cell-cycle exit and neuronal differentiation protein that has been used as a marker of surviving retinal ganglion cells (RGCs) after optic nerve injury. Thy1.1 has also been used as a marker for RGC loss, but after optic nerve crush (ONC) a decrease in Thy1.1 expression precedes the loss of RGCs.
Ahad M, Siddiqui +3 more
openaire +2 more sources
The contribution of brain reorganisation to recovery in patients with optic neuritis [PDF]
In this thesis, the mechanisms of damage and repair in clinically isolated optic neuritis (ON) were investigated in vivo, by combining magnetic resonance imaging (MRI), electrophysiology and optical coherence tomography (OCT).
Jenkins, T.M.
core
Approach to the Diagnosis and Differentiation of Glaucomatous and Nonglaucomatous Optic Neuropathies
Optic neuropathy denotes degeneration of the retinal ganglion cells with functional and structural impairment of the optic nerve. Functional damage of the optic nerve can be evaluated by checking visual acuity, color vision, pupillary function, and ...
Carmen K. M. Chan +3 more
core +1 more source
Gut microbiota regulates optic nerve fiber myelination
IntroductionRecent evidence supports the hypothesis of an association between gut microbiota and the pathogenesis of retinal and eye diseases, suggesting the existence of a gut-eye axis.
Giulia Ronchi +13 more
doaj +1 more source
Near-complete optic nerve transection by high-pressure air [PDF]
The use of high-pressure air instruments has become more common. Consequently, there have been a number of cases of orbital emphysema caused by contact with high-pressure air.
Soo Won Ko +4 more
doaj +1 more source
Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension
Glaucoma, one of the leading causes of blindness worldwide, affects primarily retinal ganglion cells (RGCs) and their axons. The pathophysiology of glaucoma is not fully understood, but it is currently believed that damage to RGC axons at the optic nerve
Manuel Vidal-Sanz +12 more
doaj +1 more source
The Time Course of Gene Expression during Reactive Gliosis in the Optic Nerve. [PDF]
Reactive gliosis is a complex process that involves changes in gene expression and morphological remodeling. The mouse optic nerve, where astrocytes, microglia and oligodendrocytes interact with retinal ganglion cell axons and each other, is a ...
Juan Qu, Tatjana C Jakobs
doaj +1 more source
Management of Ophthalmic Complications Secondary to Functional Endoscopic Sinus Surgery
Orbital complications of functional endoscopic sinus surgery (FESS) may cause irreversible damage to the orbital structures, including optic nerve, extraocular muscles, and lacrimal drainage system. The clinical diagnosis and management of these patients
Betül TUGCU +3 more
doaj +1 more source
Evaluation and management of orbital trauma
Orbital injuries occur in a variety of settings, road traffic accidents (RTA) being the commonest. Injuries vary in severity and have potential for visual impairment and disfigurement.
Kirti Nath Jha, A R Rajalakshmi
doaj +1 more source
Mechanical Study on the Traumatic Optic Nerve Injury
Optic nerve injury or blindness after head trauma has well been known since the days of Hippocrates, and has still remained one of the serious posttaumatic sequelae. Statistically about 2% of head-injured persons suffer from the visual loss and are impelled to have limited social activites3).
HIRAKAWA, Kimiyoshi +3 more
openaire +3 more sources

