Torsion-Induced Traumatic Optic Neuropathy (TITON): A physiologically relevant animal model of traumatic optic neuropathy. [PDF]
PLoS ONETraumatic optic neuropathy (TON) is a common cause of irreversible blindness following head injury. TON is characterized by axon damage in the optic nerve followed by retinal ganglion cell death in the days and weeks following injury.
Annie K Ryan +9 more
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Traumatic Optic Neuropathy. [PDF]
J Neurol Surg B Skull Base, 2021 AbstractA host of different types of direct and indirect, primary and secondary injuries can affect different portions of the optic nerve(s). Thus, in the setting of penetrating as well as nonpenetrating head or facial trauma, a high index of suspicion should be maintained for the possibility of the presence of traumatic optic neuropathy (TON).
Miller NR.
europepmc +5 more sources
Traumatic Optic Neuropathy (TON) and Ayurveda - A case report [PDF]
Journal of Ayurveda and Integrative Medicine, 2022 The vision loss in the Traumatic Optic Neuropathy is the impact of deformational forces. This occurs due to direct or indirect injuries during trauma to skull.
Pravin M. Bhat
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Cell-based therapies for traumatic optic neuropathy: Recent advances, challenges, and perspectives [PDF]
Neural Regeneration ResearchTraumatic optic neuropathy is a form of optic neuropathy resulting from trauma. Its pathophysiological mechanisms involve primary and secondary injury phases, leading to progressive retinal ganglion cell loss and axonal degeneration. Contributing factors
Yuanhui Wang +3 more
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Laser speckle contrast imaging detects relative blood flow reduction in traumatic optic neuropathy [PDF]
American Journal of Ophthalmology Case ReportsCase presentation: A 15-year-old male sustaining craniofacial injuries from a collision reported vision loss in the left eye on hospital day 12. An ophthalmologic examination revealed a visual acuity of 20/20 in the right eye and no light perception (NLP)
Mariama A. Jallow +9 more
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Mitochondrial Triglyceride Dysregulation in Optic Nerves Following Indirect Traumatic Optic Neuropathy [PDF]
Biomolecules, 2022 The purpose of this work is to identify mitochondrial optic nerve (ON) lipid alterations associated with sonication-induced traumatic optic neuropathy (TON).
Muhammad Z. Chauhan +6 more
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Traumatic Optic Neuropathy – A Conundrum [PDF]
Journal of Clinical and Diagnostic Research, 2016 Visual impairment following head injury may be an enigma especially if the onset of symptoms were to be few days after the actual trauma and the bias arising out of the initial normal ophthalmological examination is not neutralised by unbiased repeated ...
VINOTH KANNA SELVARAJ +2 more
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Traumatic optic neuropathy management: a systematic review. [PDF]
Eye (Lond)BACKGROUND: Traumatic optic neuropathy is classically described in up to 8% of patients with traumatic brain injury (TBI), but subclinical or undiagnosed optic nerve damage is much more common.
Blanch RJ, Joseph IJ, Cockerham K.
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Neuroprotective effects and mechanisms of action of artemisinin in retinal ganglion cells in a mouse model of traumatic optic neuropathy [PDF]
HeliyonIntroduction: Traumatic optic neuropathy is known to be a critical condition that can cause blindness; however, the specific mechanism underlying optic nerve injury is unclear.
Shirui Zhou +4 more
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Güncel Retina Dergisi (Current Retina Journal), 2022 Traumatic optic neuropathy (TON) is a specific neurological sequence of traumatic brain injury (TBI). It has a different mechanism than other most neurologic complications of head trauma and its consequences can be devastating. The damage can be from direct penetrating trauma or bone fracture injuring the optic nerve directly or secondary to indirect ...
Ainat, Klein,, Wahbi, ,
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