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Traumatic Optic Neuropathy: Update on Management
Encyclopedia, 2023 Traumatic optic neuropathy is one of the causes of visual loss caused by blunt or penetrating head trauma and is classified as both direct and indirect.
Mohammad Reza Hosseini Siyanaki +2 more
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Indirect traumatic optic neuropathy [PDF]
Military Medical Research, 2016 Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood, and there are no confirmed protocols for prevention, mitigation or treatment. Most data concerning this condition comes from case series of civilian patients suffering blunt injury, such as ...
Singman, Eric L. +6 more
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Traumatic Optic Neuropathy: A Review [PDF]
Craniomaxillofacial Trauma & Reconstruction, 2015 The aim of this article is to evaluate current literature on investigation and management of traumatic optic neuropathy (TON), propose recommendations for diagnosis and management, and explore novel future treatments. TON, though uncommon, causes substantial visual loss.
Arjunan Muthu, Kumaran +2 more
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BDNF and cAMP are neuroprotective in a porcine model of traumatic optic neuropathy [PDF]
JCI InsightTraumatic optic neuropathy (TON) is a devastating condition that can occur after blunt or penetrating trauma to the head, leading to visual impairment or blindness.
Kathleen Heng +12 more
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Traumatic Optic Neuropathy [PDF]
Korean Journal of Neurotrauma, 2018 Traumatic optic neuropathy (TON) refers to optic nerve injury resulting from direct and indirect head and facial trauma. The pathogenesis of indirect TON has not been fully elucidated, and the management of TON remains controversial. In this review article, I review the recent literature regarding TON and discuss how to manage indirect TON.
Yun Zhang, Meixia Zhang
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A clinical evaluation of optic neuropathy in various aetiologies
TNOA Journal of Ophthalmic Science and Research, 2023 Background: Since optic neuropathy is the initial manifestation of various systemic disorders, it is essential to do detailed investigations to arrive at the diagnosis. This aids in timely management of underlying systemic disorders and prevents not only
R Iswaria Shyamala Rani +4 more
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Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma
Neurobiology of Disease, 2020 Our goal was to investigate the neuroprotective effects of galantamine in a mouse model of blast-induced indirect traumatic optic neuropathy (bITON). Galantamine is an FDA-approved acetylcholinesterase inhibitor used to treat mild-moderate Alzheimer's ...
Sarah Naguib +4 more
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Lipidomics dataset of sonication-induced traumatic optic neuropathy in mice
Data in Brief, 2020 Traumatic optic neuropathy (TON) is the loss of vision secondary to trauma. Approximately two weeks after traumatic damage, diffuse retinal ganglion cell loss and axon degeneration of the optic nerve are exhibited [1].
Ronaldo Nuesi +4 more
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Profound vision loss impairs psychological well-being in young and middle-aged individuals. [PDF]
, 2017 PurposeThe aim of this study was to evaluate the effects of profound vision loss on psychological well-being in adolescents, young adults, and middle-aged adults with regard to mood, interpersonal interactions, and career-related goals.
Baron, David +8 more
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Why do we need optic nerve decompression of traumatic optic neuropathy patients?
Interdisciplinary Neurosurgery, 2014 Traumatic optic neuropathy can be treated by various methods including high-dose steroids and surgical decompression. Neurosurgical decompression could be required in patients with mechanical compression of the optic nerve by displaced orbital roof ...
Seong Rok Han, M.D., Ph.D.
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