Characterization of peripapillary vascular density in traumatic optic neuropathy. [PDF]
Am J Ophthalmol Case RepPurpose: Optical coherence tomography angiography is a novel imaging modality used to characterize pathologic vascular changes in the peripapillary region.
Snyder BM +4 more
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Torsion-Induced Traumatic Optic Neuropathy (TITON): A physiologically relevant animal model of traumatic optic neuropathy. [PDF]
PLoS OneTraumatic optic neuropathy (TON) is a common cause of irreversible blindness following head injury. TON is characterized by axon damage in the optic nerve followed by retinal ganglion cell death in the days and weeks following injury.
Ryan AK +9 more
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Traumatic Optic Neuropathy (TON) and Ayurveda - A case report. [PDF]
J Ayurveda Integr Med, 2022 The vision loss in the Traumatic Optic Neuropathy is the impact of deformational forces. This occurs due to direct or indirect injuries during trauma to skull.
Bhat PM.
europepmc +2 more sources
Cell-based therapies for traumatic optic neuropathy: Recent advances, challenges, and perspectives. [PDF]
Neural Regen ResTraumatic optic neuropathy is a form of optic neuropathy resulting from trauma. Its pathophysiological mechanisms involve primary and secondary injury phases, leading to progressive retinal ganglion cell loss and axonal degeneration. Contributing factors
Wang Y, Chen M, Tang Z, Gu P.
europepmc +2 more sources
A clinical evaluation of optic neuropathy in various aetiologies
TNOA Journal of Ophthalmic Science and Research, 2023 Background: Since optic neuropathy is the initial manifestation of various systemic disorders, it is essential to do detailed investigations to arrive at the diagnosis. This aids in timely management of underlying systemic disorders and prevents not only
R Iswaria Shyamala Rani +4 more
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Laser speckle contrast imaging detects relative blood flow reduction in traumatic optic neuropathy. [PDF]
Am J Ophthalmol Case RepCase presentation: A 15-year-old male sustaining craniofacial injuries from a collision reported vision loss in the left eye on hospital day 12. An ophthalmologic examination revealed a visual acuity of 20/20 in the right eye and no light perception (NLP)
Jallow MA +9 more
europepmc +2 more sources
Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma
Neurobiology of Disease, 2020 Our goal was to investigate the neuroprotective effects of galantamine in a mouse model of blast-induced indirect traumatic optic neuropathy (bITON). Galantamine is an FDA-approved acetylcholinesterase inhibitor used to treat mild-moderate Alzheimer's ...
Sarah Naguib +4 more
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Lipidomics dataset of sonication-induced traumatic optic neuropathy in mice
Data in Brief, 2020 Traumatic optic neuropathy (TON) is the loss of vision secondary to trauma. Approximately two weeks after traumatic damage, diffuse retinal ganglion cell loss and axon degeneration of the optic nerve are exhibited [1].
Ronaldo Nuesi +4 more
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Why do we need optic nerve decompression of traumatic optic neuropathy patients?
Interdisciplinary Neurosurgery, 2014 Traumatic optic neuropathy can be treated by various methods including high-dose steroids and surgical decompression. Neurosurgical decompression could be required in patients with mechanical compression of the optic nerve by displaced orbital roof ...
Seong Rok Han, M.D., Ph.D.
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Navigation-guided optic canal decompression for traumatic optic neuropathy: Two case reports
Indian Journal of Ophthalmology, 2018 Two cases of traumatic optic neuropathy presented with profound loss of vision. Both cases received a course of intravenous corticosteroids elsewhere but did not improve.
Kasturi Bhattacharjee +3 more
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