Results 51 to 60 of about 135,492 (203)
TRPV1 Tunes Optic Nerve Axon Excitability in Glaucoma
Frontiers in Physiology, 2020 The transient receptor potential vanilloid member 1 (TRPV1) in the central nervous system may contribute to homeostatic plasticity by regulating intracellular Ca2+, which becomes unbalanced in age-related neurodegenerative diseases, including Alzheimer’s
Nolan R. McGrady +3 more
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Developmental hypomyelination in Wolfram syndrome: New insights from neuroimaging and gene expression analyses [PDF]
, 2019 Wolfram syndrome is a rare multisystem disorder caused by mutations in WFS1 or CISD2 genes leading to brain structural abnormalities and neurological symptoms. These abnormalities appear in early stages of the disease.
Dougherty, Joseph +7 more
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Glial βii spectrin contributes to paranode formation and maintenance [PDF]
, 2018 Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D. +12 more
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Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma [PDF]
, 2016 BACKGROUND: This retrospective study aimed to determine how often a perimetric examination should be carried out in order to identify visual field (VF) changes in patients with relatively early manifestation glaucoma.
Abdolrahimzadeh, S +4 more
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Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases
Journal of Ophthalmology, 2012 The photopic negative response (PhNR) in response to a brief flash is a negative-going wave following the b-wave of the cone electroretinogram (ERG) that is driven by retinal ganglion cells (RGCs).
Shigeki Machida
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The role of ultrasound methods in the assessment of biometric characteristics of the optic nerve
Российский офтальмологический журнал, 2020 The diagnostics of the optic nerve (ON) pathology relies on the results of clinical and instrumental examinations, electrophysiological tests, computer tomography and magnetic resonance imaging.
T. N. Kiseleva +3 more
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Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration. [PDF]
, 2019 In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness ...
Bhattacharya, Sanjoy K +5 more
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Toward Non-Invasive Electrical Stimulation for Guided Optic Nerve Regeneration
IEEE Transactions on Neural Systems and Rehabilitation EngineeringThe optic nerve plays a critical role in visual information processing by relaying signals from the retina to the brain. Diseases affecting the optic nerve, such as glaucoma, can severely impair vision due to the nerve’s limited capacity for self ...
Pooyan Pahlavan +9 more
doaj +1 more source
Experimental and Molecular Medicine, 2019 Eye disease: switching signals for repairing injured optic nerves Regulating molecular signaling pathways that control the degradation of cellular components—a process known as autophagy—could offer a new approach to treating optic nerve damage after ...
Yao-Tseng Wen +3 more
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Ophthalmic Manifestations of Hematopoietic Malignancy
Case Reports in Ophthalmological Medicine, 2016 Purpose. To report the ocular findings in patients with hematopoietic malignancy with optic nerve involvement and abducens nerve palsy. Methods. The medical records of all cases of hematopoietic cancer with ophthalmic involvements seen in the Department ...
Natsuyo Yoshida-Hata +2 more
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