Results 81 to 90 of about 135,492 (203)

Cell Replacement Therapy for Retinal and Optic Nerve Diseases: Cell Sources, Clinical Trials and Challenges. [PDF]

Pharmaceutics, 2021
Coco-Martin RM, Pastor-Idoate S, Pastor JC.   +2 more
europepmc   +1 more source

Presumed neuroprotective therapies prescribed by veterinary ophthalmologists for canine degenerative retinal and optic nerve diseases. [PDF]

Vet Ophthalmol, 2021
Hopper RG, Montiani-Ferreira F, da Silva Pereira J, Fritz MC, Ruggiero VJ, Sapienza JS, Kato K, Komáromy AM.   +7 more
europepmc   +1 more source

Progress in Gene Therapy to Prevent Retinal Ganglion Cell Loss in Glaucoma and Leber’s Hereditary Optic Neuropathy

Neural Plasticity, 2018
The eye is at the forefront of the application of gene therapy techniques to medicine. In the United States, a gene therapy treatment for Leber’s congenital amaurosis, a rare inherited retinal disease, recently became the first gene therapy to be ...
Sara E. Ratican, Andrew Osborne, Keith R. Martin   +2 more
doaj   +1 more source

Gut microbiota regulates optic nerve fiber myelination

Frontiers in Cell and Developmental Biology
IntroductionRecent evidence supports the hypothesis of an association between gut microbiota and the pathogenesis of retinal and eye diseases, suggesting the existence of a gut-eye axis.
Giulia Ronchi, Davide Pellegrino, Marwa El Soury, Olga Amato, Francesco Gaia, Sajjad Farzin, Raffaele Nuzzi, Marijana Basic, Silvia Bolsega, Stefano Geuna, Matilde Cescon, Kirsten Haastert-Talini, Kirsten Haastert-Talini, Giovanna Gambarotta   +13 more
doaj   +1 more source

Optical Coherence Tomography Angiography in Glaucoma

Türk Oftalmoloji Dergisi, 2018
Optical coherence tomography angiography (OCTA) comprises different OCT-based technologies developed for non-invasive assessment and measurement of optic nerve head and retinal perfusion. Currently the most clinically established approach is based on the
Gábor Holló
doaj   +1 more source

OPHTHALMOSCOPIC EVALUATION OF THE OPTIC NERVE HEAD

Zdravniški Vestnik, 2002
Background. Optic nerve diseases, such as glaucomas, lead to changes in the intrapapillary and parapapillary region of the optic nerve head.Conclusions.
Marija Zupan, Kristina Mikek, Smiljana Gruden   +2 more
doaj  

Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

Neural Regeneration Research
Several studies have found that transplantation of neural progenitor cells (NPCs) promotes the survival of injured neurons. However, a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical application ...
Tong Li, Hui-Min Xing, Hai-Dong Qian, Qiao Gao, Sheng-Lan Xu, Hua Ma, Zai-Long Chi   +6 more
doaj   +1 more source

Artificial Intelligence for Screening of Multiple Retinal and Optic Nerve Diseases.

JAMA Netw Open, 2022
Dong L, He W, Zhang R, Ge Z, Wang YX, Zhou J, Xu J, Shao L, Wang Q, Yan Y, Xie Y, Fang L, Wang H, Wang Y, Zhu X, Wang J, Zhang C, Wang H, Wang Y, Chen R, Wan Q, Yang J, Zhou W, Li H, Yao X, Yang Z, Xiong J, Wang X, Huang Y, Chen Y, Wang Z, Rong C, Gao J, Zhang H, Wu S, Jonas JB, Wei WB.   +36 more
europepmc   +1 more source

Axonal mitophagy in retinal ganglion cells

Cell Communication and Signaling
Neurons, exhibiting unique polarized structures, rely primarily on the mitochondrial production of ATP to maintain their hypermetabolic energy requirements.
Yang Liang, Yulin Li, Qing Jiao, Muyang Wei, Yan Wang, Aoteng Cui, Zhihui Li, Guangyu Li   +7 more
doaj   +1 more source

Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases

Frontiers in Neurology
Growing evidence has demonstrated that peripapillary hyperreflective ovoid mass-like structures (PHOMS) are novel structures rather than a subtype of optic disc drusen.
Di Xiao, Tsering Lhamo, Yang Meng, Yishuang Xu, Changzheng Chen   +4 more
doaj   +1 more source