Results 101 to 110 of about 43,716 (252)

Relapse and Neurological Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease: A Retrospective Secondary Analysis of a Japanese Nationwide Epidemiologic Survey

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Some patients with myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) experience multiple relapses and poor prognoses; however, the factors associated with these outcomes are unclear. This study aimed to identify factors associated with relapse and neurological prognosis in patients with MOGAD.
Masashi Nakamura, Juichi Fujimori, Akiyuki Uzawa, Satoshi Kuwabara, Ichiro Nakashima   +4 more
wiley   +1 more source

The history of neuromyelitis optica [PDF]

, 2013
The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO).
Jarius, Sven, Wildemann, Brigitte
core   +1 more source

Cases of AQP4‐Antibody‐Positive Neuromyelitis Optica Spectrum Disorder Successfully Discontinuing Steroids With Satralizumab Treatment: Considerations on the Method of Tapering for Steroids After the Introduction of Satralizumab

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Satralizumab is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD). However, there are currently no standardized guidelines regarding the method or speed of steroid tapering after its introduction. In 2023, we proposed a method to commence tapering prednisolone at a rate of 1 mg every 4 weeks, starting 8 weeks ...
Kiyotaka Nakamagoe, Mayuko Tanaka, Kota Igari, Tetsu Suzuki, Shinji Saiki   +4 more
wiley   +1 more source

An unusual case of optic and chiasmal neuritis caused by hypersensitivity to mycobacterium: A case report [PDF]

Journal of Krishna Institute of Medical Sciences University
We describe Magnetic Resonance Imaging (MRI) findings in a 49-years-old female who presented with subacute visual loss. MRI findings were suggestive of optic neuritis and chiasmal neuritis. She had necrotic mediastinal lymphadenopathy which was diagnosed
Reetika Kapoor, Parag Patil, Rushikesh Naik, Varsha Rangankar   +3 more
doaj  

Quantifying visual pathway axonal and myelin loss in multiple sclerosis and neuromyelitis optica

NeuroImage: Clinical, 2016
Background: The optic nerve is frequently injured in multiple sclerosis and neuromyelitis optica, resulting in visual dysfunction, which may be reflected by measures distant from the site of injury.
Praveena Manogaran, Irene M. Vavasour, Alex P. Lange, Yinshan Zhao, Katrina McMullen, Alexander Rauscher, Robert Carruthers, David K.B. Li, Anthony L. Traboulsee, Shannon H. Kolind   +9 more
doaj   +1 more source

The diagnostic and prognostic value of neurofilament heavy chain levels in immune-mediated optic neuropathies [PDF]

, 2012
Background. Loss of visual function differs between immune-mediated optic neuropathies and is related to axonal loss in the optic nerve. This study investigated the diagnostic and prognostic value of a biomarker for neurodegeneration, the neurofilament ...
Petzold, A, Plant, GT
core   +4 more sources

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

Equine Veterinary Education, Volume 38, Issue 5, Page e235-e242, May 2026.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch, C. Frank, J. B. Daniels, E. Acutt, E. Contino   +4 more
wiley   +1 more source

Case report: HLA-B35-associated optic neuritis

Frontiers in Ophthalmology
PurposeTo describe a unique presentation of optic neuritis associated with positive HLA-B35.ObservationsA woman presented with unilateral retro-orbital pain, mildly decreased vision, and optic disc edema with new-onset aphthous ulcers.
Florian H. Guillot, Andrew R. Carey
doaj   +1 more source

Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination. [PDF]

, 2018
OBJECTIVE: We characterised the clinical course, treatment and outcomes in 59 patients with relapsing myelin oligodendrocyte glycoprotein (MOG) antibody-associated demyelination.
Australasian and New Zealand MOG Study Group Andrews, P, Barnett, Mh, Barton, J, Brilot, F, Broadley, S, Burrow, J, Butzkueven, H, Cairns, A, Calvert, S, Caruana, P, Chelakkadan, S, Clark, D, Dale, Rc, Fraser, C, Freeman, J, Fung, Vsc, Gill, D, Grattan-Smith, P, Gupta, S, Hardy, T, Henderson, Apd, Kothur, K, Lechner-Scott, J, Ling, S, Lopez, J, Malone, S, Marriott, M, Merheb, V, Mohammad, S, Nguyen, Tk, Nosadini, M, O'grady, G, Orr, C, Ouvrier, R, Parratt, J, Patrick, E, Pilli, D, Ramanathan, S, Reddel, Sw, Riminton, D, Riney, K, Rodriguez-Casero, V, Ryan, M, Scheffer, I, Shah, U, Shuey, N, Spooner, C, Subramanian, G, Tantsis, E, Tea, F, Thomas, T, Thompson, J, Troedson, C, Vucic, S, Ware, T, Webster, R, White, Ob, Yiannikas, C, Yiu, E, Zou, A.   +59 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 665-675, April 2026.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source