Results 91 to 100 of about 232,897 (244)

An unusual case of optic and chiasmal neuritis caused by hypersensitivity to mycobacterium: A case report [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University
We describe Magnetic Resonance Imaging (MRI) findings in a 49-years-old female who presented with subacute visual loss. MRI findings were suggestive of optic neuritis and chiasmal neuritis. She had necrotic mediastinal lymphadenopathy which was diagnosed
Reetika Kapoor   +3 more
doaj  

Case report: HLA-B35-associated optic neuritis

open access: yesFrontiers in Ophthalmology
PurposeTo describe a unique presentation of optic neuritis associated with positive HLA-B35.ObservationsA woman presented with unilateral retro-orbital pain, mildly decreased vision, and optic disc edema with new-onset aphthous ulcers.
Florian H. Guillot, Andrew R. Carey
doaj   +1 more source

Top‐Down CSF Peptidomics Reveals Disease‐Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease‐related biological processes, thus
Cristina Contini   +9 more
wiley   +1 more source

Optic neuritis as an early sign of multiple sclerosis

open access: yes, 2016
Nilufer Kale Department of Neurology, Bakirkoy Prof Dr Mazhar Osman Training and Research Hospital, Istanbul, Turkey Abstract: Optic neuritis (ON) is an acute inflammatory demyelinating disorder of the optic nerve. The general characteristics of isolated
Kale N
core  

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith ...
Shun Zhou   +16 more
wiley   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

open access: yesBrain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu   +11 more
wiley   +1 more source

Quantifying visual pathway axonal and myelin loss in multiple sclerosis and neuromyelitis optica

open access: yesNeuroImage: Clinical, 2016
Background: The optic nerve is frequently injured in multiple sclerosis and neuromyelitis optica, resulting in visual dysfunction, which may be reflected by measures distant from the site of injury.
Praveena Manogaran   +9 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu   +5 more
wiley   +1 more source

VER in optic neuritis.

open access: yesIndian journal of ophthalmology, 1989
A prospective study was carried out on 27 patients with optic neuritis. Besides detailed clinical examination, visual evoked responses (VER) were studied utilising the checker board pattern reversal and flash stimuli. The recording with the 30 minute check size was found to be the most consistent both for the controls and the patients. Flash evoked VER
Menon Vimala, Kumar Harsh, Prakash Prem
openaire   +2 more sources

p‐Brain: A Modular Open‐Source Framework for Automated Quantitative DCE‐MRI of Cerebral Perfusion, Microvasculature, and Blood–Brain Barrier Permeability

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 6, Page 2601-2614, December 2026.
ABSTRACT We present p‐Brain, a modular, open‐source framework for reproducible, automated quantitative DCE‐MRI at scale. Rather than a fixed pipeline, p‐Brain is built from interchangeable stages (ingestion, T1/M0$$ {T}_1/{M}_0 $$ fitting, vascular and tissue ROI extraction, signal‐to‐concentration conversion, kinetic modeling, and quality control ...
Edis D. Tireli   +5 more
wiley   +1 more source

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