Results 51 to 60 of about 347,881 (287)

Relapse Patterns in NMOSD: Evidence for Earlier Occurrence of Optic Neuritis and Possible Seasonal Variation

open access: yesFrontiers in Neurology, 2020
Neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS) show overlap in their clinical features. We performed an analysis of relapses with the aim of determining differences between the two conditions.
E. Khalilidehkordi   +65 more
semanticscholar   +1 more source

Pediatric optic neuritis [PDF]

open access: yesCase reports, 2019
Optic neuritis in the pediatric population greatly differs from its presentation in the adult population. Firstly, it is usually bilateral in children and mostly unilateral in adults. (1,2,3) Second, it is generally associated with inflammation of the optic disc in pediatrics (1,2,3), whereas the inflammation is often retrobulbar in adults. (2) Finally,
openaire   +3 more sources

“Optic neuritis” that is neither [PDF]

open access: yesNeurology Clinical Practice, 2013
A 28-year-old African American woman developed periocular pain worsening with eye movement and decreased vision in her left eye. A diagnosis of left optic neuropathy was made based on the findings of decreased vision in the left eye, a left relative afferent pupillary defect, and mild optic disc hyperemia in the left eye (figure 1), with normal retinae
Nancy J. Newman   +3 more
openaire   +3 more sources

Pediatric optic neuritis [PDF]

open access: yesNeurology, 2016
Optic neuritis (ON) is a common presenting symptom in pediatric CNS demyelinating disorders and may be associated with dramatic visual loss. Knowledge regarding clinical presentation, associated diseases, therapy, and outcomes in ON in children has grown over the past decade. These studies have shown that younger children (
Jennifer Graves   +4 more
openaire   +3 more sources

Optic Neuritis

open access: yesContinuum, 2019
This article discusses the clinical presentation, evaluation, and management of the patient with optic neuritis. Initial emphasis is placed on clinical history, examination, diagnostic testing, and medical decision making, while subsequent focus is placed on examining specific inflammatory optic neuropathies.
openaire   +3 more sources

Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis. However, sIL‐2R has so far not been evaluated in these conditions.
Philipp Klyscz   +8 more
wiley   +1 more source

Superficial Macula Capillary Complexity Changes Are Associated With Disability in Neuromyelitis Optica Spectrum Disorders

open access: yesFrontiers in Neurology, 2021
Purpose: We examined the macular microvascular changes of the macula in neuromyelitis optica spectrum disorder (NMOSD) patients and its association with their disability and other clinical variables.Methods: Thirty-four NMOSD (13 patients without optic ...
Ruili Wei   +7 more
doaj   +1 more source

Volumetric MRI Comparing Longitudinal Change in MOGAD to NMOSD, MS and Healthy Controls, and Disability Associations

open access: yesAnnals of Neurology, EarlyView.
Objectives To examine volumetric magnetic resonance imaging (vMRI) in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), compared to multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and healthy controls (HC). Methods Standardized vMRI in MOGAD were compared to age, sex, and disease duration matched MS (5:1),
Amy Kunchok   +10 more
wiley   +1 more source

Clinical and paraclinical characteristics of optic neuritis in the context of the McDonald criteria 2017

open access: yesScientific Reports
Optic neuritis is often an initial symptom in multiple sclerosis (MS) or clinically isolated syndrome (CIS), yet comprehensive studies using the 2017 McDonald criteria for MS are scarce. Patient records from our academic centre (2010–2018) were reviewed.
Konstantin F. Jendretzky   +13 more
doaj   +1 more source

New optical coherence tomography biomarker for diagnosis of acute optic neuritis in multiple sclerosis

open access: yesHeliyon
Objectives: Is imaging of retrolaminar optic nerve, during attack of acute optic neuritis in multiple sclerosis valuable? Methods: This is a prospective observational Case series study. Twenty two patients recruited from Al-Azhar University Hospitals and
Hend Mohammed Safwat   +2 more
doaj   +1 more source

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