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OCT-Based Differentiation of First Acute Optic Neuritis: An International Study of 111 Patients With NMOSD and MOGAD. [PDF]
Pakeerathan T +42 more
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Updated recommendations from the Optic Neuritis Treatment Trial.
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Design, methods, and conduct of the optic neuritis treatment trial
Contemporary Clinical Trials, 1993The Optic Neuritis Treatment Trial (ONTT) was an investigator-initiated, multi-centered, randomized, controlled clinical trial supported by cooperative agreements and grants. It was designed to evaluate the efficacy and safety of oral prednisone or intravenous methylprednisolone followed by oral prednisone as compared with oral placebo.
Patricia A Cleary, Roy W Beck
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American Journal of Ophthalmology, 2004
To assess visual function more than 10 years after an episode of optic neuritis in patients enrolled in the Optic Neuritis Treatment Trial.Longitudinal follow-up of a randomized clinical trial.Vision testing included measures of visual acuity, contrast sensitivity, and visual field.
Robin L Gal +2 more
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To assess visual function more than 10 years after an episode of optic neuritis in patients enrolled in the Optic Neuritis Treatment Trial.Longitudinal follow-up of a randomized clinical trial.Vision testing included measures of visual acuity, contrast sensitivity, and visual field.
Robin L Gal +2 more
exaly +3 more sources
Experience of the optic neuritis treatment trial
Current Neurology and Neuroscience Reports, 2004James Corbett
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The Optic Neuritis Treatment Trial: Implications for Clinicians
Seminars in Ophthalmology, 1995(1995). The Optic Neuritis Treatment Trial: Implications for Clinicians. Seminars in Ophthalmology: Vol. 10, No. 3, pp. 214-220.
B, Katz, J D, Trobe, R W, Beck
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Prepublication Blackout in the Optic Neuritis Treatment Trial
Archives of Ophthalmology, 1994Notwithstanding the cautionary comments of Silberberg, 1 the conclusion that high-dose intravenous methylprednisolone followed by a course of oral prednisolone after a bout of acute optic neuritis will reduce the rate of development of multiple sclerosis (MS) over a 2-year period (in patients with white-matter lesions on magnetic resonance imaging) was
M L, Slavin, R M, Burde
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Optic Neuritis Treatment Trial
Archives of Ophthalmology, 1993To determine the efficacy of corticosteroids as treatment for acute demyelinative optic neuritis after completion of 1 year of patient follow-up in the Optic Neuritis Treatment Trial.Randomized placebo controlled multicenter clinical trial.Fifteen university or hospital-based centers throughout the United States.Four hundred fifty-seven patients with ...
R W, Beck, P A, Cleary
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Cerebrospinal fluid in acute optic neuritis
Neurology, 1996The Optic Neuritis Treatment Trial (ONTT) is a prospective study of corticosteroid treatment of acute optic neuritis (ON), with subsequent longitudinal follow-up to determine development of clinically definite multiple sclerosis (CDMS). We analyzed the CSF of 83 patients with clinically isolated ON who underwent lumbar puncture within 24 hours of ...
L A, Rolak +5 more
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