Results 41 to 50 of about 318,136 (246)

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Optic disc pit: A review

, 2010
Background: Since Wiethe first described the clinical presentation of two optic disc depressions in a 62-year-old woman in 1882, there have been many studies addressing what later become known as the "optic disc pit." The main complication of ...
Georgopoulos, G., Georgalas, I., Petrou, P., Ladas, I.   +3 more
core   +1 more source

Progressive optic nerve changes in cavitary optic disc anomaly: integration of copy number alteration and cis-expression quantitative trait loci to assess disease etiology

BMC Medical Genetics, 2019
Background We performed clinical and genetic characterization of a family with cavitary optic disc anomaly (CODA), an autosomal dominant condition that causes vision loss due to adult-onset maculopathy in the majority of cases. CODA is characterized by a
Eileen S. Hwang, Denise J. Morgan, Katie L. Pennington, Leah A. Owen, John H. Fingert, Paul S. Bernstein, Margaret M. DeAngelis   +6 more
doaj   +1 more source

Congenital Optic Nerve Pit in Trisomy 18

, 2013
The authors report the first case of trisomy 18 associated with a clinically detectable optic nerve pit. A female infant with a birth weight of 2,150 g was born by cesarean section to a healthy 40-year-old woman at 38 weeks of gestation.
Ditte J. Hess, Audina M. Berrocal, Chang, Jonathan S, Jonathan S. Chang, Villegas, Victor M, Victor M. Villegas, Berrocal, Audina M, Hess, Ditte J   +7 more
core   +1 more source

Automatic Lesion Morphometrics Reliably Predict Sensorimotor Recovery After Spinal Cord Injury: A Longitudinal, Multicenter Neuroimaging Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate automatic magnetic resonance imaging (MRI)‐derived lesion morphometrics against manual measurements and their prognostic value for characterizing distinct acute to chronic neurological recovery trajectories after spinal cord injury (SCI). Methods We studied a retrospective, multicenter cohort of cervical and thoracolumbar
Dario Pfyffer, Jan Valošek, Lynn Farner, Enamundram Naga Karthik, Gergely David, Norbert Weidner, Rainer Abel, Doris Maier, Armin Curt, Margret Hund‐Georgiadis, Mirko Aach, Michael Baumberger, Julien Cohen‐Adad, Patrick Freund, the Nogo Inhibition in Spinal Cord Injury Study Group, Rainer Abel, Kerstin Rehahn, Mirko Aach, Klaus Röhl, Norbert Weidner, Marion Saur, Nikolaus Weiskopf, Doris Maier, Andreas Badke, Margret Hund‐Georgiadis, Michael Baumberger, Armin Curt, Jesus Benito‐Penalva, Jiri Kriz   +28 more
wiley   +1 more source

Minimally invasive procedure for optic disc pit maculopathy: vitrectomy with scleral plug and analysis on pattern of resolution

Scientific Reports, 2023
Optic disc pit maculopathy (ODP-M) is a rare complication of optic disc pit which can cause irreversible visual impairment. The aim of this study is to evaluate the anatomical and functional outcomes and pattern of resolution of ODP-M following ...
Anadi Khatri, Saurav Man Shrestha, Gunjan Prasai, Kamal Pandit, Priya Bajgai, Rupesh Agrawal, Vishali Gupta   +6 more
doaj   +1 more source

INVERTED INTERNAL LIMITING MEMBRANE-FLAP TECHNIQUE FOR OPTIC DISK PIT MACULOPATHY: MORPHOLOGIC AND FUNCTIONAL ANALYSIS

, 2021
To analyze morphologic and functional changes after inverted internal limiting membrane-flap technique for optic disk pit maculopathy using optical coherence tomography, multifocal electroretinography, and ...
Giovanni Alessio, Alessandra Sborgia, Alfredo Niro, Luigi Sborgia, Giancarlo Sborgia, Nicola Recchimurzo, Marina Piepoli   +6 more
core   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

Optical Coherence Tomography of a Coexisting Optic Nerve Cyst and Optic Disc Pit: A Case Report

Kaohsiung Journal of Medical Sciences, 2010
We describe a rare case of an optic pit located over the nasal portion of the disc that was independent of a coexisting optic nerve cyst. A healthy 35-year-old patient was referred to our clinic seeking alternative treatment options because his previous ...
Tzu-Lun Huang, Kuan-Hung Lin, Min-Muh Sheu, Rong-Kung Tsai   +3 more
doaj   +1 more source