Results 41 to 50 of about 5,483 (255)
Bezmiâlem ScienceOptic disc pit is an excavation of the optic disc that usually develops congenital or rarely acquired, mostly located in the inferotemporal part of the disc. It is usually asymptomatic but sometimes might be symptomathic with maculopathy development.
Atilla ŞAHİN +2 more
doaj +1 more source
BMC Medical Genetics, 2019 Background We performed clinical and genetic characterization of a family with cavitary optic disc anomaly (CODA), an autosomal dominant condition that causes vision loss due to adult-onset maculopathy in the majority of cases. CODA is characterized by a
Eileen S. Hwang +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Scientific Reports, 2023 Optic disc pit maculopathy (ODP-M) is a rare complication of optic disc pit which can cause irreversible visual impairment. The aim of this study is to evaluate the anatomical and functional outcomes and pattern of resolution of ODP-M following ...
Anadi Khatri +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Optical Coherence Tomography of a Coexisting Optic Nerve Cyst and Optic Disc Pit: A Case Report
Kaohsiung Journal of Medical Sciences, 2010 We describe a rare case of an optic pit located over the nasal portion of the disc that was independent of a coexisting optic nerve cyst. A healthy 35-year-old patient was referred to our clinic seeking alternative treatment options because his previous ...
Tzu-Lun Huang +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
Oftalʹmologiâ, 2014 We report two cases of an 18-year-old boy with a left optic disc pit and associated retinal edema of the macula and 47-year-old woman with an optic disk pit and associated retinal detachment of the macula.
S. V. Sdobnokova +2 more
doaj +3 more sources
Optic Disc Imaging by Heidelberg Retinal Tomogram in Congenital Optic Disc Anomaly
Indian Journal of Ophthalmology, 2004 We evaluated two cases of congenital optic disc anomaly with the Heidelberg Retinal Tomograph (HRT) that could be mistaken for glaucomatous optic disc. One was an optic disc coloboma with a visual field defect and the other had an optic disc pit without ...
Kunjam Vallam, Sekhar G
doaj
Surgical Management of Optic Disc Pit Maculopathy with Outer Retinal Hole
Case Reports in Ophthalmology, 2012 Objective: To report the successful outcome of a rare optic pit-associated maculopathy with an outer retinal hole following 23 G vitrectomy, internal limiting membrane (ILM) peeling and fluid-gas exchange without additional endolaser.
Aditya Shreekant Kelkar +3 more
doaj +1 more source