Results 101 to 110 of about 78,872 (276)

Continuous variable quantum computation with spatial degrees of freedom of photons

, 2011
We discuss the use of the transverse spatial degrees of freedom of photons propagating in the paraxial approximation for continuous variable information processing. Given the wide variety of linear optical devices available, a diverse range of operations
Gomes, R. M., Ribeiro, P. H. Souto, Tasca, D. S., Toscano, F., Walborn, S. P.   +4 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Current and Nascent SETI Instruments [PDF]

, 2011
Here we describe our ongoing efforts to develop high-performance and sensitive instrumentation for use in the search for extra-terrestrial intelligence (SETI).
Chen, Henry, Cobb, Jeff, Cordes, Jim, Filiba, Terry, Foster, Griffin, Fries, Adam, Howard, Andrew, Korpela, Eric, Lebofsky, Matt, McMahon, Peter L., Parsons, Aaron, Siemion, Andrew P. V., Spitler, Laura, von Korff, Josh, Wagner, Mark, Werthimer, Dan   +15 more
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Thin-film lithium niobate photonic circuit for ray tracing acceleration

Nature Communications
Real-time, physically realistic rendering is a significant challenge in spatial computing systems due to the excessive computational intensity of ray tracing and the performance limitations of current electronic platform. Here, we propose and demonstrate
Shiji Zhang, Zixi liu, Xueyi Jiang, Haojun Zhou, Bo Wu, Hailong Zhou, Bo Xu, Qing Zhu, Yuhao Guo, Cheng Zeng, Jinsong Xia, Jianji Dong, Xinliang Zhang   +12 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Spectral convolutional neural network chip for in-sensor edge computing of incoherent natural light

Nature Communications
Optical neural networks are considered next-generation physical implementations of artificial neural networks, but their capabilities are limited by on-chip integration scale and requirement for coherent light sources.
Kaiyu Cui, Shijie Rao, Sheng Xu, Yidong Huang, Xusheng Cai, Zhilei Huang, Yu Wang, Xue Feng, Fang Liu, Wei Zhang, Yali Li, Shengjin Wang   +11 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

All-optical analog differential operation and information processing empowered by meta-devices

Nanophotonics
The burgeoning demand for high-performance computing, robust data processing, and rapid growth of big data necessitates the emergence of novel optical devices to efficiently execute demanding computational processes.
Zhou Chen, Wang Yongtian, Huang Lingling
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source