Results 111 to 120 of about 2,198,954 (282)

Repeatability and agreement in optical biometry of a new swept-source optical coherence tomography–based biometer versus partial coherence interferometry and optical low-coherence reflectometry [PDF]

, 2016
PurposeTo estimate the repeatability of biometric parameters obtained with a new swept-source biometer and to compare the agreement with that of partial coherence interferometry (PCI) and optical low-coherence reflectometry (OLCR).SettingDepartment of ...
Büehren, Tobias, Blum, Marcus, Sekundo, Walter, Kunert, Kathleen S., Haigis, Wolfgang, Schütze, Juliane, Peter, Monika   +6 more
core   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Development of the guideline for optical biometry in ophthalmology

, 2021
Objetivo: Desenvolver um guia que auxilie a tomada de decisão do examinador nos procedimentos operacionais da biometria óptica em condições oculares especiais.
Pannunzio, Rafael [UNIFESP]
core  

Optical Label Switching Functionalities Employing Semiconductor Optical Amplifiers [PDF]

, 2006
Optical labelling of data packets enables high router throughputs. Semiconductor optical amplifiers (SOAs) are key building blocks to implement the functionalities required for fast optical label ...
Vegas Olmos, J.J., E. van Breusegem, KOONEN, A, Olmos, J. J. Vegas, YAN, N, C. Peucheret, Koonen, A. M. J., A.M.J. Koonen, Breusegem, E., Yan, N., Van Breusegem, Erik, J. J. Vegas Olmos, TAFUR MONROY, I, Peucheret, Christophe, Peucheret, C., N. Yan, Tafur Monroy, I.; id_orcid, Tafur Monroy, I., PEUCHERET, C, Tafur Monroy, Idelfonso, VEGAS OLMOS, J, Koonen, A.M.J., Breusegem, van, E., I. Tafur Monroy   +23 more
core   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

Force measurements with optical tweezers inside living cells [PDF]

, 2014
The force exerted by optical tweezers can be measured by tracking the momentum changes of the trapping beam, a method which is more general and powerful than traditional calibration techniques as it is based on first principles, but which has not been ...
Farre, A., Martin-Badosa, E., Josep Mas, Jordi Sancho-Parramon, Arnau Farré, Sancho-Parramon, J., Montes-Usategui, M., Mario Montes-Usategui, Mas, J., Estela Martín-Badosa   +9 more
core   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

British Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said, Robert B. de Mooij, Dian Jiao, Reitze J. Ovelgonne, Rami Biram, Juan Delgado‐SanMartin, Alexander M. K. Rothman, Sofia S. Villar, Andreas A. Roussakis, Jurjan Aman, Ron A. A. Mathôt, Eleonora L. Swart, Martin R. Wilkins, Imke H. Bartelink   +13 more
wiley   +1 more source

Applanation Ultrasound versus Optical Biometry in the measurement of Axial Length in a Normal Eye [PDF]

Objectives Accurate measurement of the axial length (AL) of the eye is important to make sure that the patient is emmetropic postoperatively. Multiple studies conducted around the globe compare AL using optical and ultrasound biometry.
Shaista Haider, M. Azam Khan, Maria Saleem, Arsh Zahoor, Irfan Aslam Khattak, Ayisha Shakeel   +5 more
core   +1 more source

High sensitivity optical coherence detector optimization [PDF]

, 2001
An optimal optical filtering scheme for an optical coherence detection system gives very high detection sensitivities (-30dB) for a partially coherent source.
Coutinho, R.C., French, H.A., Selviah, D.R., H.D. Griffiths, R.C. Coutinho, H.A. French, Griffiths, H.D., D.R. Selviah   +7 more
core   +1 more source