Results 121 to 130 of about 2,013 (228)

Glycative Stress Disrupts the Mitochondrial‐Lysosome Axis and Promotes Geroconversion in Aging Cardiomyocytes

Aging Cell, Volume 25, Issue 3, March 2026.
Cardiac aging promotes mitochondrial AGE accumulation driven by defective glycative stress detoxification. AGE‐modified mitochondria disrupt lysosomal proteolysis, impairing mitophagy and promoting lipofuscin buildup. This mechanism sustains chronic unresolved mitochondrial damage, driving proinflammatory senescence in cardiomyocytes and defining a ...
Diana Bou‐Teen, Simonas Valiuska, Elisabet Miro‐Casas, Chiara Rubeo, Elena Bonzon‐Kulichenko, Zuzana Nichtova, Celia Fernandez‐Sanz, Javier Inserte, Antonio Rodriguez‐Sinovas, Begoña Benito, Eduard Ródenas‐Alesina, Jesús Vázquez, Ignacio Ferreira‐González, Marisol Ruiz‐Meana   +13 more
wiley   +1 more source

Automated information extraction from plant specimen labels using OCR and large language models. [PDF]

Biodivers Data J
Wen J.
europepmc   +1 more source

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

Cell Proliferation, Volume 59, Issue 3, March 2026.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie, Yu Wang, Wenjie Cheng, Minbo Yan, Kunyu Li, Xiang Wu, Jiaqing Wu, Zhuangzhuang Zhang, Yingbo Dai   +8 more
wiley   +1 more source

Astrocyte Bioenergetic Remodeling as a Central Trait of Disrupted Glucocorticoid Signaling: Mechanisms and Implications for Stress Vulnerability

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Low/brief glucocorticoid (GC) elevations can enhance mitochondrial output (↑ oxygen consumption rate, OCR; ↑ mitochondrial membrane potential, ΔΨm) and Ca2+ buffering, in part via glucocorticoid receptor (GR) trafficking to mitochondria in complexes with Bcl2 and Bag1.
Paweł Hanus, Dorota Frydecka, Michał Ślęzak   +2 more
wiley   +1 more source

VI-OCR: "Visually Impaired" optical character recognition pipeline for text accessibility assessment. [PDF]

Sci Rep
Gao Q, Manduchi R, Ramulu PY, Legge GE, Xiong Y.   +4 more
europepmc   +1 more source

Advanced deep learning techniques for automated license plate recognition. [PDF]

Sci Rep
Meesad P, Thumthong W.
europepmc   +1 more source

Deep inception neural network with residual connections for Tamil handwritten character recognition. [PDF]

Sci Rep
Periyasamy H, Natarajan S, Amirtharajan R.   +2 more
europepmc   +1 more source

Deep convolutional neural network for isolated Arabic handwritten character recognition: design, evaluation, and comparative study. [PDF]

Sci Rep
Attar ET.
europepmc   +1 more source

Automated Detection of Digital Alcohol Marketing Using SCANNER: An Integrated Deep-Learning Approach. [PDF]

Drug Alcohol Rev
Martino F, Liyana Pathirana N, Saif L, Bhatti A, Backholer K.   +4 more
europepmc   +1 more source

Automated segmentation and quantitative measurement of cervical nerves in ultrasound images using an SZJ-SEG-based deep learning framework. [PDF]

Quant Imaging Med Surg
Zhang Z, Cao W, Luan H, Lin J, Zhu X, Yan Z, Wang J, Zhang H, Guo R, Bai Z.   +9 more
europepmc   +1 more source