Results 91 to 100 of about 154,999 (331)

PDZK1 Protects Against RPE Senescence by Targeting the 14‐3‐3ε‐mTOR Axis to Attenuate Early Diabetic Retinopathy

Advanced Science, EarlyView.
PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao, Junbiao Zhang, Yanli Liu, Lili Wang, Chunxi Huang, Wei Chi, Meixia An   +6 more
wiley   +1 more source

Regulating the Interaction Between Near‐Infrared Dye and Endogenous Albumin for Concurrent Imaging Skin Inflammation and Neovascularization After Flap Transplantation

Aggregate, EarlyView.
This study identified a near‐infrared (NIR) dye with superior covalent albumin‐binding capability, enabling high‐contrast imaging of skin inflammation with minimal background interference. This work further demonstrated dual‐channel imaging of skin barrier disruption and neovascularization in flap transplantation models, and allowed simultaneous ...
Yijing Du, Xue Zheng, Yanli Gao, Zetao Dang, Yuewei Zhang, Shoujun Zhu   +5 more
wiley   +1 more source

Handheld optical coherence tomography angiography

Biomedical Optics Express, 2017
We developed a handheld optical coherence tomography angiography (OCTA) system using a 100-kHz swept-source laser. The handheld probe weighs 0.4 kg and measures 20.6 × 12.8 × 4.6 cm3. The system has dedicated features for handheld operation. The probe is equipped with a mini iris camera for easy alignment. Real-time display of the en face OCT and cross-
Jianlong Yang, David Huang, Liang Liu, Gangjun Liu, J. Peter Campbell   +4 more
openaire   +3 more sources

Self‐Supervised Learning‐Based Framework for Speckle Reduction of Optical Coherence Tomography Images Using Frame Interpolation

Advanced Intelligent Systems, EarlyView.
In summary, a self‐supervised end‐to‐end framework for OCT image despeckling is proposed, without access to unpaired noisy–clean images or paired noisy–noisy images for training. The despeckling performance has been evaluated on 150 subjects from five retina datasets (121 subjects) and one middle ear dataset (29 subjects). Optical coherence tomography (
Zhiyi Jiang, Yifeng Hao, Jing Dai, Ka‐Wai Kwok   +3 more
wiley   +1 more source

Macular telangiectasia with bilateral obliterated capillaries: a case report

Journal of Medical Case Reports, 2022
Background We report an otherwise healthy adult with macular telangiectasia with aneurysms, ischemia, and obliterated capillaries in both eyes. Methods This is a case report with a brief literature review.
Melika Samadi, Afsaneh Azarkish, Hamid Riazi-Esfahani, Alireza Mahmoudi, Nazanin Ebrahimiadib   +4 more
doaj   +1 more source

Advances in Doppler optical coherence tomography and angiography [PDF]

Translational Biophotonics, 2019
AbstractSince the first demonstration of Doppler optical coherence tomography (OCT) in 1997, several functional extensions of Doppler OCT have been developed, including velocimetry, angiogram, and optical coherence elastography. These functional techniques have been widely used in research and clinical applications, particularly in ophthalmology. Here,
Yan Li, Jason Chen, Zhongping Chen
openaire   +5 more sources

Mainstream Artificial Intelligence Technologies in Contemporary Ophthalmology

Advanced Intelligent Systems, EarlyView.
This review explores the latest artificial intelligence (AI) technologies in ophthalmology, focusing on four key data types: medical imaging, electronic health records, robotic‐assisted surgery, and genomics. It examines the structural features, use cases, clinical goals, and evaluation metrics of various AI algorithms, while also introducing emerging ...
Shiqi Yin, Lei Wang, Shanjun Wu, Jiewei Jiang, Wei Qiang, Yangyang Wang, Shihong Wang, Yi Shao, Wei Chen, Zhongwen Li   +9 more
wiley   +1 more source

Multimodal images of chronic branch retinal vein occlusion

International Medical Case Reports Journal, 2017
Stephen G Schwartz, Armando Monroig, Harry W Flynn Jr Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: Two illustrative cases of chronic branch retinal vein occlusion ...
Schwartz SG, Monroig A, Flynn HW Jr
doaj  

Optical coherence tomography angiography of the macula and optic nerve head: microvascular density and test-retest repeatability in normal subjects

BMC Ophthalmology, 2018
Background Despite the potential usefulness of optical coherence tomography angiography in retinal and optic disc conditions, the reliability of the imaging modality remains unclear.
Ching Wei Lim, Jun Cheng, Elton Lik Tong Tay, Hwei Yee Teo, Elizabeth Poh Ying Wong, Vernon Khet Yau Yong, Boon Ang Lim, Owen Kim Hee, Hon Tym Wong, Leonard Wei Leon Yip   +9 more
doaj   +1 more source

A New Approach in Risk Stratification by Coronary CT Angiography. [PDF]

, 2014
For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks.
Budoff, Matthew J, Nakanishi, Rine
core   +3 more sources