Results 141 to 150 of about 150,755 (325)

circSIRT2/miR‐542‐3p/VASH1 axis regulates endothelial‐to‐mesenchymal transition (EndMT) in subretinal fibrosis in age‐related macular degeneration models

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
circSIRT2 inhibited SRF by binding miR‐542‐3p, which stimulated the VASH1 expression and subsequently suppressed EndMT. The circSIRT2/miR‐542‐3p/VASH1 axis may serve as a promising therapeutic target for SRF in nAMD. Abstract Neovascular age‐related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading ...
Min Zhang   +8 more
wiley   +1 more source

Influence of scleral thickness on photodynamic therapy outcomes in central serous chorioretinopathy

open access: yesActa Ophthalmologica, Volume 103, Issue 3, Page e165-e175, May 2025.
Abstract Purpose To test the prognostic role of anterior scleral substantia propria (ASSP) thickness in predicting the 3‐month response after half‐dose photodynamic therapy (PDT) in central serous chorioretinopathy (CSCR) and to assess its clinical relevance of ASSP in different CSCR phenotypes.
Paolo Forte   +11 more
wiley   +1 more source

Optical Coherence Tomography Angiography in Optic Nerve Drusen

open access: yesOphthalmic Research, 2017
<b><i>Aim:</i></b> To determine the efficacy of optical coherence tomography angiography (OCT-A) in diagnosing optic nerve head flow impairment in patients with optic nerve drusen. <b><i>Methods:</i></b> Patients affected by optic-nerve head drusen (ONHD) attending the Eye Clinic of the Federico II ...
Cennamo, Gilda   +5 more
openaire   +3 more sources

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao   +5 more
wiley   +1 more source

Morpho-functional evaluation of torpedo maculopathy with optical coherence tomography angiography and microperimetry

open access: yesAmerican Journal of Ophthalmology Case Reports, 2018
Purpose: To report the case of a 13-year-old girl with torpedo maculopathy, evaluated with multimodal morpho-functional retinal imaging, including fundus photography, infra-red and blue fundus autofluorescence, swept-source optical coherence tomography ...
Gabriela Grimaldi   +4 more
doaj  

Choroidal neovascularization associated with combined hamartoma of retina and retinal pigment epithelium: Multimodal imaging

open access: yesIndian Journal of Ophthalmology, 2018
Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) has been considered as a congenital benign entity with evidence of choroidal neovascularization membranes (CNVM) being associated with it in literature.
Rajan Gupta   +3 more
doaj   +1 more source

Automatic measurement of choroidal thickness with swept-source optical coherence tomography for clinical follow-up in acute Vogt-Koyanagi-Harada disease [PDF]

open access: yes
Background: The course of acute Vogt-Koyanagi-Harada is typically assessed qualitatively using indocyanine green angiography. Swept-source optical coherence tomography may provide a safer, non-invasive, more objective approach to follow up. In this study,
Arias Barquet, Lluís   +5 more
core   +1 more source

Optical coherence tomography angiography for the anterior segment

open access: yesEye and Vision, 2019
Optical coherence tomography angiography (OCTA) is a rapid and non-invasive technique for imaging vasculature in the eye. As OCTA can produce high-resolution cross-sectional images and allow depth-resolved analysis for accurate localization of pathology of interest, it has become a promising method for anterior segment imaging. Furthermore, OCTA offers
Marcus Ang   +9 more
openaire   +4 more sources

Comparative efficacy of intravitreal anti‐VEGF therapy for neovascular age‐related macular degeneration: A systematic review with network meta‐analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract The aim of this review was to evaluate the comparative efficacy of intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy for neovascular AMD. We searched 12 literature databases for randomised clinical trials (RCT) on anti‐VEGF therapy for neovascular AMD and extracted data on: change from baseline to 12 months in best ...
Emilie T. S. Butler   +17 more
wiley   +1 more source

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