Results 51 to 60 of about 648,123 (291)

Spatiotemporal communication with synchronized optical chaos

, 2000
We propose a model system that allows communication of spatiotemporal information using an optical chaotic carrier waveform. The system is based on broad-area nonlinear optical ring cavities, which exhibit spatiotemporal chaos in a wide parameter range ...
A. Amengual, C. R. Mirasso, D. W. McLaughlin, D. W. McLaughlin, G. D. VanWiggeren, G. D. VanWiggeren, G. Pérez, H. D. I. Abarbanel, I. Fischer, J. García-Ojalvo, J. H. Xiao, J. K. White, J. P. Goedgebuer, J. V. Moloney, K. Ikeda, K. Ikeda, K. M. Cuomo, L. Junge, L. Kocarev, L. Kocarev, L. Kocarev, L. M. Pecora, M. Haeltermann, M. Le Berre, M. Le Berre, M. Sauer, M. Sauer, P. Colet, Rajarshi Roy, S. Boccaletti, S. Sivaprakasam, Y. Jiang, Y. Liu   +32 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Why compensating fibre nonlinearity will never meet capacity demands [PDF]

, 2015
Current research efforts are focussed on overcoming the apparent limits of communication in single mode optical fibre resulting from distortion due to fibre nonlinearity.
Alvarado, Alex, Bayvel, Polina, Lavery, Domanic, Maher, Robert, Millar, David, Savory, Seb J.   +5 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

High-Sensitive Refractive Index Sensing Enabled by Topological Charge Evolution

IEEE Photonics Journal, 2020
A high-sensitive refractive index sensor is proposed and demonstrated by utilizing merging bound states in the continuum, namely a set of integer topological charges in the momentum space.
Jiaxin Lv, Zihao Chen, Xuefan Yin, Zixuan Zhang, Weiwei Hu, Chao Peng   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Enhanced Neural Architecture for Real-Time Deep Learning Wavefront Sensing

Sensors
To achieve real-time deep learning wavefront sensing (DLWFS) of dynamic random wavefront distortions induced by atmospheric turbulence, this study proposes an enhanced wavefront sensing neural network (WFSNet) based on convolutional neural networks (CNN).
Jianyi Li, Qingfeng Liu, Liying Tan, Jing Ma, Nanxing Chen   +4 more
doaj   +1 more source

Design and Analysis of Novel O-Band Low Polarization Sensitive SOA Co-Integrated With Passive Waveguides for Optical Systems

IEEE Photonics Journal, 2022
Low polarization-dependent semiconductor optical amplifiers (SOAs) with an easy fabrication process and the capability to be co-integrated with passive elements are crucial in photonic integrated circuits.
Aref Rasoulzadeh Zali, Ripalta Stabile, Nicola Calabretta   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source